Electrochemical Decarboxylative Minisci-Type Acylation of Quinoxalines under Catalyst- and External-Oxidant-Free Conditions

被引：4
|
作者：
Li, Yongmei [1 ,2 ]
Liang, Sen [1 ]
Wang, Dehui [2 ]
Xu, Kun [2 ]
Zeng, Chengchu [2 ]
机构：
[1] Beijing Technol & Business Univ, Beijing Key Lab Flavor Chem, Beijing 100048, Peoples R China
[2] Beijing Univ Technol, Fac Environm & Life, Beijing 100124, Peoples R China
来源：
SYNTHESIS-STUTTGART | 2023年 / 55卷 / 18期
基金：
北京市自然科学基金; 中国国家自然科学基金;
关键词：
electrosynthesis; Minisci reaction; acyl radical; & alpha; -keto acids; anodic oxidation; N-HETEROCYCLES;
D O I：
10.1055/a-2147-2863
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
An electrochemical approach for the Minisci-type acylation of quinoxalines with a-keto acids as the acyl radical precursors is reported. With the assistance of TFA as the key additive, acylated quinoxalines were constructed in synthetically useful yields. The distinguishable features of this electrochemical protocol include catalyst-and external oxidant-free conditions, and operational simplicity.
引用
收藏
页码：3026 / 3032
页数：7
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