PHARMACOLOGICAL CONTAMINANTS IN AQUATIC ECOSYSTEMS

被引:0
|
作者
Curis, Cecilia [1 ]
Rosca, Ramona Oana [2 ]
Moroianu, Lavinia-Alexandra [3 ]
Plesea, Alina [1 ]
Tribus, Laura-Carina [4 ]
Serboiu, Crenguta [5 ]
Stoica, Roxana-Adriana [5 ]
Mahler, Beatrice [5 ]
机构
[1] Dunarea de Jos Univ Galati, Fac Med & Pharm, Med Dept, 47 Domneasca St, Galati, Romania
[2] Dunarea de Jos Univ Galati, Fac Med & Pharm, Pharmaceut Sci Dept, 47 Domneasca St, Galati, Romania
[3] Dunarea de Jos Univ Galati, Fac Med & Pharm, Clin Med Dept, 47 Domneasca St, Galati, Romania
[4] Carol Davila Univ Med & Pharm Bucharest, Fac Dent Med, 37 Dionisie Lupu St, Bucharest, Romania
[5] Carol Davila Univ Med & Pharm Bucharest, 37 Dionisie Lupu St, Bucharest, Romania
关键词
contaminants; ecosystems; profiles; risk; ANTICANCER DRUGS; RISK-ASSESSMENT; ANTIBIOTICS; PHARMACEUTICALS; WATER; RIVER; LAKES;
D O I
10.31925/farmacia.2024.1.4
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
This study emphasises the need for ecological risk profiles based on geographic and pharmaceutical class criteria. Establishing these profiles is vital for identifying contamination sources, assessing levels, and implementing strategies to neutralise negative ecosystem impacts. Failure to do so may transform therapeutic agents into catalysts for new pathologies with potentially catastrophic consequences. Risks are amplified as the life cycle of pharmaceuticals impacting "non-target" organisms generates biologically active metabolites with similar ecosystem risks. This growing concern, spurred by pharmaceutical industry advancements, requires attention from researchers studying aquatic ecosystem stability. Authored by medical practitioners, this article serves as a cautionary message to the medical community disputing polypharmacy and the looming global iatrogenic threat to pharmacological contaminants. Consequently, the training of future healthcare professionals must incorporate education on pharmacological contaminants as an integral component of continuous medical education. Failure to do so may leave future doctors grappling with a complex pathology that is difficult to estimate and undoubtedly challenging to treat. This study offers both theoretical and didactic perspectives, proving valuable for clinical practice. Practitioners must proactively inform patients during daily practice to mitigate polypharmacy and prevent health issues, safeguarding against harmful effects.
引用
收藏
页码:44 / 59
页数:16
相关论文
共 50 条
  • [41] FUNGI IN THE MONITORING OF AQUATIC ECOSYSTEMS
    TEREKHOVA, VA
    MIKOLOGIYA I FITOPATOLOGIYA, 1995, 29 (01): : 36 - 40
  • [42] Viruses and prophages in aquatic ecosystems
    Sime-Ngando, Telesphore
    Colombet, Jonathan
    CANADIAN JOURNAL OF MICROBIOLOGY, 2009, 55 (02) : 95 - 109
  • [43] DIVERSITY AND STRUCTURE IN AQUATIC ECOSYSTEMS
    FRONTIER, S
    OCEANOGRAPHY AND MARINE BIOLOGY, 1985, 23 : 253 - 312
  • [44] Linkages among aquatic ecosystems
    Lamberti, Gary A.
    Chaloner, Dominic T.
    Hershey, Anne E.
    JOURNAL OF THE NORTH AMERICAN BENTHOLOGICAL SOCIETY, 2010, 29 (01): : 245 - 263
  • [45] Effect of antibiotics on diverse aquatic plants in aquatic ecosystems
    Li, Yiting
    Zhang, Yani
    Wang, Dongyao
    Zhao, Jiamei
    Yu, Huan
    Chen, Yun
    Yang, Jiqiang
    AQUATIC TOXICOLOGY, 2025, 281
  • [46] Invasion and predation in aquatic ecosystems
    Weis, Judith S.
    CURRENT ZOOLOGY, 2011, 57 (05) : 613 - 624
  • [47] Disinfection threatens aquatic ecosystems
    Zhang, Hong
    Tang, Wenzhong
    Chen, Yushun
    Yin, Wei
    SCIENCE, 2020, 368 (6487) : 146 - 147
  • [48] THE FATE OF ENDOSULFAN IN AQUATIC ECOSYSTEMS
    PETERSON, SM
    BATLEY, GE
    ENVIRONMENTAL POLLUTION, 1993, 82 (02) : 143 - 152
  • [49] ANTHROPOGENIC IMPACT ON AQUATIC ECOSYSTEMS
    STUMM, W
    NATURWISSENSCHAFTEN, 1977, 64 (04) : 157 - 165
  • [50] A MACROPHYTE SUBMODEL FOR AQUATIC ECOSYSTEMS
    COLLINS, CD
    WLOSINSKI, JH
    AQUATIC BOTANY, 1989, 33 (3-4) : 191 - 206