A Case Report and Literature Review of the Role of Dupilumab in the Management of Lichen Planus: Cause or Treatment?

被引：1
|
作者：
Gajraj, Farrah A. [1 ]
Zahir, Jamal [2 ]
Adereti, Christopher [2 ]
Gajraj, Mohamed H. [3 ]
机构：
[1] Ross Univ, Sch Med, Med, Miramar, FL 33027 USA
[2] Ross Univ, Sch Med, Surg, Miramar, FL USA
[3] Coral Springs Med Grp, Med, Coral Springs, FL USA
来源：
CUREUS JOURNAL OF MEDICAL SCIENCE | 2023年 / 15卷 / 07期
关键词：
lichenified drug eruption; t-cell-mediated immune response; autoimmune-mediated inflammatory dermatosis; interleukin-4; interleukin; 13; drug-induced lp; atopic dermatitis; dupilumab; lichen planus; DERMATITIS;
D O I：
10.7759/cureus.41274
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Lichen planus (LP) is a chronic inflammatory skin condition characterized by the six Ps (ie. purple, planar, polygonal, pruritic, plaques, and papules) often causing physical, emotional, and psychological stress for the person affected. Drug-induced LP has been described after the administration of drugs like antihypertensives, non-steroidal anti-inflammatory drugs (NSAIDs), and biologics like adalimumab and etanercept. Currently, there is a dearth of studies discussing the association between LP and dupilumab. Here, we present the case of a young adult female who developed LP 24 months after treatment with dupilumab for severe atopic dermatitis. We also conducted a review of the literature discussing the association between LP and dupilumab.
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页数：8
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