A Case Report and Literature Review of the Role of Dupilumab in the Management of Lichen Planus: Cause or Treatment?

被引：1

作者：

Gajraj, Farrah A. ^{[1
]}

Zahir, Jamal ^{[2
]}

Adereti, Christopher ^{[2
]}

Gajraj, Mohamed H. ^{[3
]}

机构：

[1] Ross Univ, Sch Med, Med, Miramar, FL 33027 USA

[2] Ross Univ, Sch Med, Surg, Miramar, FL USA

[3] Coral Springs Med Grp, Med, Coral Springs, FL USA

来源：

CUREUS JOURNAL OF MEDICAL SCIENCE | 2023年 / 15卷 / 07期

关键词：

lichenified drug eruption; t-cell-mediated immune response; autoimmune-mediated inflammatory dermatosis; interleukin-4; interleukin; 13; drug-induced lp; atopic dermatitis; dupilumab; lichen planus; DERMATITIS;

D O I：

10.7759/cureus.41274

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Lichen planus (LP) is a chronic inflammatory skin condition characterized by the six Ps (ie. purple, planar, polygonal, pruritic, plaques, and papules) often causing physical, emotional, and psychological stress for the person affected. Drug-induced LP has been described after the administration of drugs like antihypertensives, non-steroidal anti-inflammatory drugs (NSAIDs), and biologics like adalimumab and etanercept. Currently, there is a dearth of studies discussing the association between LP and dupilumab. Here, we present the case of a young adult female who developed LP 24 months after treatment with dupilumab for severe atopic dermatitis. We also conducted a review of the literature discussing the association between LP and dupilumab.

引用

页数：8

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