NfL makes regulatory debut as neurodegenerative disease biomarker

被引：22

作者：

Mullard, Asher

机构：

来源：

NATURE REVIEWS DRUG DISCOVERY | 2023年 / 22卷 / 06期

关键词：

D O I：

10.1038/d41573-023-00083-z

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

The FDA approved tofersen for amyotrophic lateral sclerosis based on the drug’s ability to lower blood levels of neurofilament light (NfL) — establishing a proof of potential for this neuroscience biomarker that could have implications for other diseases of the brain.

引用

页码：431 / 434

页数：4

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