Single Cell Multi-Omic Dissection of Response and Resistance to Chimeric Antigen Receptor T Cells Against BCMA in Relapsed Multiple Myeloma

被引：2

作者：

Merz, Maximilian ^{[1
]}

Fischer, Luise ^{[2
]}

Sia, Jaren ^{[3
]}

Born, Patrick ^{[1
]}

Weiss, Ronald ^{[2
]}

Grieb, Nora ^{[1
]}

Rade, Michael ^{[4
]}

Boldt, Andreas ^{[2
]}

Fricke, Stephan ^{[5
]}

Franz, Paul ^{[4
]}

Scolnick, Jonathan ^{[3
]}

Venkatraman, Lakshmi ^{[3
]}

Xu, Stacy ^{[3
]}

Kloetzer, Christina ^{[1
]}

Heyn, Simone ^{[1
]}

Kubasch, Anne Sophie ^{[6
]}

Baber, Ronny ^{[7
]}

Wang, Song Yau ^{[2
]}

Bach, Enrica ^{[1
]}

Hoffmann, Sandra ^{[1
]}

Ussmann, Jule ^{[1
]}

Metzeler, Klaus H. ^{[1
]}

Herling, Marco ^{[1
]}

Herling, Carmen ^{[1
]}

Jentzsch, Madlen ^{[1
]}

Franke, Georg-Nikolaus ^{[1
]}

Sack, Ulrich ^{[2
]}

Koehl, Ulrike ^{[4
]}

Reiche, Kristin ^{[4
]}

Platzbecker, Uwe ^{[8
]}

Vucinic, Vladan ^{[1
]}

机构：

[1] Univ Leipzig, Dept Hematol Cellular Therapy Hemostaseol & Infec, Med Ctr, Leipzig, Germany

[2] Univ Leipzig, Leipzig, Germany

[3] Singleron Biotechnol, Singapore, Singapore

[4] Fraunhofer IZI, Leipzig, Germany

[5] Fraunhofer Inst Cell Therapy & Immunol IZI, Leipzig, Germany

[6] Univ Hosp Leipzig, Dept Hematol, Dresden, Germany

[7] Univ Leipzig, Inst Lab Med Clin Chem & Mol Diagnost, Med Ctr, Leipzig, Germany

[8] Univ Hosp Leipzig, Dept Hematol, Leipzig, Germany

来源：

BLOOD | 2023年 / 142卷

关键词：

D O I：

10.1182/blood-2023-187371

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页数：4

共 50 条

[21] Chimeric antigen receptor T cell therapies for multiple myeloma
Wu, Chao
Zhang, Lina
Brockman, Qierra R.
Zhan, Fenghuang
Chen, Lijuan
JOURNAL OF HEMATOLOGY & ONCOLOGY, 2019, 12 (01)
[22] Chimeric antigen receptor T cell therapy for multiple myeloma
Hasegawa, Kana
Hosen, Naoki
INFLAMMATION AND REGENERATION, 2019, 39 (1)
[23] Chimeric antigen receptor T cell therapies for multiple myeloma
Chao Wu
Lina Zhang
Qierra R. Brockman
Fenghuang Zhan
Lijuan Chen
Journal of Hematology & Oncology, 12
[24] PHASE I, OPEN-LABEL TRIAL OF ANTI-BCMA CHIMERIC ANTIGEN RECEPTOR T CELLS IN PATIENTS WITH RELAPSED/REFRACTORY MULTIPLE MYELOMA
Zhang, W.
Zhao, W.
Liu, J.
He, A.
Chen, Y.
Cao, X.
Yang, N.
Wang, B.
Zhang, P.
Zhang, Y.
Wang, F.
Lei, B.
Gu, L.
Yang, Y.
Bai, J.
Zhang, R.
Wang, X.
Ma, X.
Wang, J.
Wang, J.
Wei, L.
Zhang, J.
Zang, X.
Zhuang, Q.
Fan, F. X.
HAEMATOLOGICA, 2017, 102 : 2 - 3
[25] Effective Treatment of Relapsed/Refractory Multiple Myeloma Including Extramedullary Involvement By BCMA-Specific Chimeric Antigen Receptor-Modified T Cells
Mi, Jian-Qing
Fan, Xiaohu
Xu, Jie
Liu, Yuanfang
Zhuang, Yan
Yang, Shuangshuang
Zhang, Wu
Chen, Bing
Wang, Yueying
Weng, Xiangqin
Li, Junmin
Fu, Weijun
Jiang, Hua
Zhu, Li
Chen, Zhu
Chen, Sai-Juan
Hou, Jian
BLOOD, 2017, 130
[26] A Multi-Omic Single-Cell Landscape of Cytokine Release Syndrome in Multiple Myeloma Patients after Anti-BCMA CAR-T Cell Therapy
Hu, Yongxian
Li, Xia
Jiang, Penglei
Yang, Tingting
Gu, Tianning
Si, Xiaohui
Xie, Yali
Zhang, Mingming
Wei, Guoqing
Xu, Huijun
Cen, Zenan
Cui, Jiazhen
Huang, Simao
Ni, Fang
Wang, Linqin
Wang, Xiujian
Zeng, Xiangjun
Kong, Delin
Zhao, Houli
Chang, Alex H.
Zhang, Yanlei
Zhang, Jin
Huang, Jinyan
Qian, Pengxu
Huang, He
BLOOD, 2023, 142
[27] Epigenetic Modifications As a Mechanism of Resistance to BCMA-Directed Immunotherapies in Multiple Myeloma: Insights from Multi-Omic Profiling
Haertle, Larissa
Cuenda, Natalia Buenache
Diaz, Isabel Espejo
Del Campo, Paula Lazaro
Arroyo-Barea, Andres
Rieger, Leonie
Rosa-Rosa, Juan Manuel
Fernandez, Rafael Alonso
Lopez, Nieves
Sanchez-Pina, Jose
Garcia-Ortiz, Almudena
Valeri, Antonio
Barrio, Santiago
Al-Shahrour, Fatima
Bassermann, Florian
Martinez-Lopez, Joaquin
Di Domenico, Tomas
BLOOD, 2024, 144 : 5794 - 5795
[28] Treatment of relapsed or refractory multiple myeloma with bb2121 chimeric antigen receptor T cells
Stocker, Nicolas
HEMATOLOGIE, 2021, 27 (02): : 46 - 47
[29] Current advances in chimeric antigen receptor T-cell therapy for refractory/relapsed multiple myeloma
Huang, He
uW, Heng-wei
Hu, Yong-xian
JOURNAL OF ZHEJIANG UNIVERSITY-SCIENCE B, 2020, 21 (01): : 29 - 41
[30] Cardiovascular events during treatment with anti-BCMA chimeric antigen receptor T-cells in multiple myeloma
Mathilde, Chanut
HEMATOLOGIE, 2023, 29 (05): : 274 - 275

← 1 2 3 4 5 →