Disease burden of bacteraemia with extended-spectrum beta-lactamase-producing and Enterobacterales in Korea

被引:2
|
作者
Lee, C. M. [1 ]
Lee, S. [2 ,3 ]
Kim, E. S. [4 ]
Kim, H. B. [4 ]
Park, W. B. [1 ,7 ]
Moon, S. M. [4 ,5 ]
Kim, Y. K. [6 ,10 ]
Park, K. -H. [5 ]
Kwak, Y. G. [8 ]
Kim, B. [9 ]
Kim, Y. S.
Kim, C-J. [11 ]
Gil, H-Y. [12 ]
Ahn, J. [13 ,15 ]
Song, K-H. [4 ,14 ]
机构
[1] Seoul Natl Univ, Coll Med, Dept Internal Med, Seoul, South Korea
[2] Pusan Natl Univ, Dept Internal Med, Sch Med, Pusan, South Korea
[3] Pusan Natl Univ Hosp, Med Res Inst, Pusan, South Korea
[4] Seoul Natl Univ, Bundang Hosp, Dept Internal Med, Coll Med, Seongnam, South Korea
[5] Hallym Univ, Sacred Heart Hosp, Dept Internal Med, Anyang, South Korea
[6] Yonsei Univ, Wonju Coll Med, Dept Internal Med, Wonju, South Korea
[7] Chonnam Natl Univ, Med Sch, Dept Infect Dis, Gwangju, South Korea
[8] Inje Univ, Ilsan Paik Hosp, Dept Internal Med, Goyang, South Korea
[9] Hanyang Univ, Coll Med, Dept Internal Med, Seoul, South Korea
[10] Chungnam Natl Univ, Div Infect Dis, Sch Med, Daejeon, South Korea
[11] Ewha Womans Univ, Coll Med, Dept Internal Med, Seoul, South Korea
[12] Pfizer Pharmaceut Korea Ltd, Real World Evidence Team, Seoul, South Korea
[13] Ewha Womans Univ, Dept Hlth Convergence, Seoul, South Korea
[14] Seoul Natl Univ, Dept Internal Med, Bundang Hosp, 82,Gumi ro 173 Beon gil, Seongnam 13620, Gyeonggi Do, South Korea
[15] Ewha Womans Univ, Dept Hlth Convergence, 52 Ewhayeodae Gil, Seoul 03760, South Korea
关键词
Bacteraemia; Extended-spectrum beta-lactamase; Carbapenem-resistant; Enterobacterales; ESCHERICHIA-COLI; RISK-FACTORS; INFECTION; OUTCOMES; IMPACT; COLONIZATION;
D O I
10.1016/j.jhin.2023.11.013
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
Background: Despite the significant impact of multi-drug-resistant bacteraemia, especially extended-spectrum beta-lactamase-producing Enterobacterales (ESBL-E) and carbapenem-resistant Enterobacterales (CRE), the burden of disease has not been investigated thoroughly. Aim: To evaluate the clinical outcomes and socio-economic burden of ESBL-E and CRE bacteraemia nationwide in the Republic of Korea. Methods: A search was undertaken for all cases of ESBL-E and CRE bacteraemia and matched controls in 10 hospitals in the Republic of Korea over 6 months. Patients with ESBL-E or CRE bacteraemia were classified as the R group, and matched controls with antibiotic-susceptible bacteraemia and without infection were classified as the S and N groups, respectively. Patients' clinical data were collected, and the economic burden was estimated based on medical expenses, loss of productivity and total costs.
引用
收藏
页码:85 / 93
页数:9
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