1,6-Addition Reactions of Difluoroenol Silyl Ethers with Benzoquinones and Quinonediimines To Access Difluorooxymethyl and Difluoroaminomethyl Compounds

被引：3
|
作者：
Hong, Peng [1 ,2 ,3 ]
Xu, Jinjing [1 ,2 ]
Li, Jinshan [1 ,2 ]
Zhu, Xiaolei [1 ,2 ]
Ying, Anguo [3 ]
Wang, Zhiming [1 ,2 ]
Yang, Jianguo [1 ,2 ]
机构：
[1] Taizhou Univ, Adv Res Inst, Jiaojiang 318000, Zhejiang, Peoples R China
[2] Taizhou Univ, Sch Pharmaceut Sci, Jiaojiang 318000, Zhejiang, Peoples R China
[3] Qufu Normal Univ, Dept Chem & Chem Engn, Qufu 273100, Shandong, Peoples R China
来源：
ADVANCED SYNTHESIS & CATALYSIS | 2023年 / 365卷 / 24期
关键词：
1,6-Addition; Difluoroenol Silyl Ethers; Benzoquinones; Quinonediimines; Hexafluoroisopropanol; ENOL ETHERS; ASYMMETRIC-SYNTHESIS; EFFICIENT; QUINONES; ALCOHOLS; ANALOGS; WATER; SITE;
D O I：
10.1002/adsc.202300877
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
The etherification and amination of difluoroenol silyl ethers with benzoquinones and quinonediimines were achieved by using hexafluoroisopropanol (HFIP) as the solvent. This 1,6-addition reaction could construct difluorooxymethyl and difluoroaminomethyl compounds under metal-free conditions. It is preliminarily speculated that the reaction took place through a single electron transfer (SET) process. image
引用
收藏
页码：4550 / 4555
页数：6
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