SUSTAINED IL-6 SECRETION CAN LEAD TO AN AMPLIFIED INFLAMMATORY RESPONSE, MEDIATED BY THE ACTIVATION OF STAT3 AND NFKB VIA THE IL-6 AMPLIFIER LOOP

被引：0
|
作者：
Singh, Mantabya [1 ]
Prasad, Narayan [1 ]
Agarwal, Vikas [2 ]
Rai, Mohit [2 ]
机构：
[1] SGPGIMS, Nephrol, Lucknow, Uttar Pradesh, India
[2] SGPGIMS, Clin Immunol & Rheumatol, Lucknow, Uttar Pradesh, India
来源：
NEPHROLOGY DIALYSIS TRANSPLANTATION | 2023年 / 38卷
关键词：
D O I：
暂无
中图分类号：
R3 [基础医学]; R4 [临床医学];
学科分类号：
1001 ; 1002 ; 100602 ;
摘要：
5108
引用
收藏
页码：I915 / I915
页数：1
相关论文
共 50 条
  • [1] STAT3 activation in response to IL-6 is prolonged by the binding of IL-6 receptor to EGF receptor
    Wang, Yuxin
    van Boxel-Dezaire, Anette H. H.
    Cheon, HyeonJoo
    Yang, Jinbo
    Stark, George R.
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2013, 110 (42) : 16975 - 16980
  • [2] Hepatoprotection via the IL-6/Stat3 pathway
    Taub, R
    JOURNAL OF CLINICAL INVESTIGATION, 2003, 112 (07): : 978 - 980
  • [3] Thienotriazolopyrimidine Derivatives Inhibit STAT3 Activation Induced by IL-6
    Lee, Seung Woong
    Oh, Hyun-Mee
    Rho, Mun-Chual
    Song, Yang-Heon
    BULLETIN OF THE KOREAN CHEMICAL SOCIETY, 2014, 35 (08) : 2570 - 2572
  • [4] Immune Exhaustion And Il-6/stat3 Activation In Ipf Lymphocytes
    Young, A.
    Shaginurova, G.
    Kropski, J. A.
    Blackwell, T. S.
    Drake, W.
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2016, 193
  • [5] The role of IL-6 and STAT3 in inflammation and cancer
    Hodge, DR
    Hurt, EM
    Farrar, WL
    EUROPEAN JOURNAL OF CANCER, 2005, 41 (16) : 2502 - 2512
  • [6] GPER protein mediated IL-6/STAT3 signaling pathway activation in endometrial carcinoma
    Li, L.
    Jun, Z.
    INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER, 2016, 26 : 1022 - 1022
  • [7] CONSTITUTIVE ACTIVATION OF STAT3 IN RHEUMATOID ARTHRITIS CORRELATES WITH IL-6 LEVELS
    Isomaki, P.
    Junttila, I.
    Vidqvist, K. -L.
    Korpela, M.
    Silvennoinen, O.
    ANNALS OF THE RHEUMATIC DISEASES, 2014, 73 : 370 - 370
  • [8] Over Activation of IL-6/STAT3 Signaling Pathway in Juvenile Dermatomyositis
    Zheng, Qi
    Wang, Zhaoling
    Tan, Yejun
    Zhu, Kun
    Lu, Meiping
    RHEUMATOLOGY AND THERAPY, 2024, 11 (05) : 1255 - 1269
  • [9] A role of IL-1 and p38 MAPK in inhibition of IL-6 mediated Stat3 activation
    Ahmed, ST
    Ivashkiy, LB
    FASEB JOURNAL, 1999, 13 (05): : A1148 - A1148
  • [10] Synthesis of Thienopyrimidine Derivatives as Inhibitors of STAT3 Activation Induced by IL-6
    Jang, Hyun-Jae
    Kim, Sung Min
    Rho, Mun-Chual
    Lee, Seung Woong
    Song, Yang-Heon
    JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY, 2019, 29 (06) : 856 - 862
12345