New dimeric sesquiterpenoids from the whole plant of Artemisia sieversiana

被引：4
|
作者：
Dong, Jun-yi [1 ]
Cai, Yu-xing [1 ]
Li, Ya-lin [1 ]
Zhang, Yu-xin [1 ]
Yu, Zhan-peng [1 ]
Kong, Ling-yi [1 ]
Luo, Jian-guang [1 ]
机构：
[1] China Pharmaceut Univ, Sch Tradit Chinese Pharm, State Key Lab Nat Med, Jiangsu Key Lab Bioact Nat Prod Res, 24 Tong Jia Xiang, Nanjing 210009, Peoples R China
来源：
PHYTOCHEMISTRY LETTERS | 2023年 / 55卷
关键词：
Artemisia sieversiana; Dimeric sesquiterpenoids; Compositae; IL-6 inhibitory activity; GUAIANOLIDES;
D O I：
10.1016/j.phytol.2023.04.005
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
Two new dimeric sesquiterpenoids (1 and 2) were obtained from the whole plant of Artemisia sieversiana. The structures of these new sesquiterpenoids were characterized by the comprehensive analysis of IR NMR spectra, and HRESIMS data. Compounds 1 and 2 exhibited inhibitory activities in the production of IL-6 at the con-centration of 80 mu M (49.1% and 39.0%, respectively).
引用
收藏
页码：97 / 100
页数：4
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