As summarized herein, CC is part of the exposome and has both direct and indirect effects on environmental exposures and human health. Through a number of interconnected pathways, CC can have significant effects on the onset of allergies and related respiratory disorders and may pose a challenge for allergic individuals by enhancing propensity to exacerbation of their existing allergies. EC can have particular impacts on vulnerable populations, such as the elderly, children, or pregnant women, who may have weaker immune systems, higher sensitivity, or lower access to resources. Individuals and populations need to take action to protect themselves from EC, such as by reducing their exposure, enhancing their resilience, or advocating for policies that mitigate environmental hazards.