Cs2CO3-Promoted [3+2] Cyclization of Chalcone and N-Tosylhydrazone

被引：0
|
作者：
He, Jing [1 ]
Liu, Yali [1 ]
Feng, Yijiao [1 ]
Li, Xuezhen [1 ]
Liu, Ping [1 ]
Dai, Bin [1 ]
机构：
[1] Shihezi Univ, Sch Chem & Chem Engn, Key Lab Green Proc Chem Engn Xinjiang Bingtuan, Shihezi 832004, Peoples R China
来源：
POLYCYCLIC AROMATIC COMPOUNDS | 2023年 / 43卷 / 04期
基金：
中国国家自然科学基金;
关键词：
Chalcone; cyclization; N-tosylhydrazone; FULLY SUBSTITUTED PYRAZOLES; TRANSITION-METAL; 3-COMPONENT REACTION; EFFICIENT; FUNCTIONALIZATION; CONSTRUCTION; HYDRAZINES; ALDEHYDES;
D O I：
10.1080/10406638.2022.2078845
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Cs2CO3-promoted [3 + 2] cyclization of chalcone and N-tosylhydrazones has been developed, a series of novel (4,5-diaryl-1H-pyrazol-3-yl)(aryl)methanone derivatives were synthesized with a wide range of substrates, good tolerance of functional groups and by a one-pot three-component reaction of chalcone, aryl formaldehyde, and TsNHNH2. In addition, the gram-scale synthesis of the product and further transformations were also investigated.
引用
收藏
页码：3827 / 3839
页数：13
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