Two-phase Porous Media Flow Model Based on the Incompressible Navier-Stokes Equation

被引:1
|
作者
Ma, Hui [1 ]
Kinzer-Ursem, Tamara L. [1 ]
Linnes, Jacqueline C. [1 ]
机构
[1] Purdue Univ, Weldon Sch Biomed Engn, W Lafayette, IN 47907 USA
基金
美国国家科学基金会; 美国国家卫生研究院;
关键词
RICHARDS EQUATION; WASHBURN EQUATION; PAPER; PERMEABILITY; SATURATION; TRANSPORT; DEVICES; WATER; ASSAY;
D O I
10.1021/acs.analchem.3c05982
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
Two-phase porous media flow is important in many applications from drug delivery to groundwater diffusion and oil recovery and is of particular interest to biomedical diagnostic test developers using cellulose and nitrocellulose membranes with limited fluid sample volumes. This work presents a new two-phase porous media flow model based on the incompressible Navier-Stokes equation. The model aims to address the limitations of existing methods by incorporating a partial saturation distribution in porous media to account for limited fluid volumes. The basic parameters of the model are the pore size distribution and the contact angle. To validate the model, we solved five analytical solutions and compared them to corresponding experimental data. The experimentally measured penetration length data agreed with the model predictions, demonstrating model accuracy. Our findings suggest that this new two-phase porous media flow model can provide a valuable tool for researchers developing fluidic assays in paper and other porous media.
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页码:5265 / 5273
页数:9
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