Recent Advances in Pectin-based Nanoencapsulation for Enhancing the Bioavailability of Bioactive Compounds: Curcumin Oral Bioavailability

被引:15
|
作者
Dib, Thamila [1 ]
Pan, Haibo [1 ]
Chen, Shiguo [1 ]
机构
[1] Zhejiang Univ, Coll Biosyst Engn & Food Sci, Zhejiang R&D Ctr Food Technol & Equipment, Fuli Inst Food Sci,Zhejiang Key Lab Agrofood Proc, Hangzhou 310058, Peoples R China
基金
中国国家自然科学基金;
关键词
Pectin; carrier agent; nanoencapsulation; curcumin; bioactive compounds; SOLID LIPID NANOPARTICLES; EMULSION-STABILIZING PROPERTIES; DRUG-DELIVERY; ELECTROSTATIC INTERACTION; NANO-ENCAPSULATION; AQUEOUS SOLUBILITY; SUSTAINED-RELEASE; BEET PECTIN; FOOD; POLYSACCHARIDES;
D O I
10.1080/87559129.2021.2012796
中图分类号
TS2 [食品工业];
学科分类号
0832 ;
摘要
Curcumin has gained much attention due to its wide range of health-benefiting effects. However, its low oral bioavailability hampers its use as bioactive compound for functional foods. Nanoencapsulation is a common technique for improving bioavailability of bioactive compounds. Pectin is one of the most common carriers for curcumin. This review highlights a recent advance in pectin-based nanoencapsulation techniques for the entrapment of various bioactive components. Furthermore, interest is on the entrapment of curcumin in pectin-based nanoparticles, as well as its release profile. Moreover, an addition of natural polymers (polysaccharides and/or proteins) can improve the properties of pectin nano-carriers.
引用
收藏
页码:3515 / 3533
页数:19
相关论文
共 50 条
  • [21] Emulsion systems stabilized with biopolymers to enhance oral bioaccessibility and bioavailability of lipophilic bioactive compounds
    Anal, Anil K.
    Boonlao, Nuntarat
    Ruktanonchai, Uracha R.
    [J]. CURRENT OPINION IN FOOD SCIENCE, 2023, 50
  • [22] Improving the Oral Bioavailability of Curcumin Using Novel Organogel-Based Nanoemulsions
    Yu, Hailong
    Huang, Qingrong
    [J]. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2012, 60 (21) : 5373 - 5379
  • [23] Recent advances in nanoencapsulation of hydrophobic marine bioactives: Bioavailability, safety, and sensory attributes of nano-fortified functional foods
    Hosseini, Seyed Fakhreddin
    Ramezanzade, Leila
    McClements, David Julian
    [J]. TRENDS IN FOOD SCIENCE & TECHNOLOGY, 2021, 109 : 322 - 339
  • [24] Recent advances in emerging pectin-derived nanocarriers for controlled delivery of bioactive compounds
    Huang, Meigui
    Sun, Yan
    Tan, Chen
    [J]. FOOD HYDROCOLLOIDS, 2023, 140
  • [25] Development of Lipid-Based Nanoparticles for Enhancing the Oral Bioavailability of Paclitaxel
    Pandita, Deepti
    Ahuja, Alka
    Lather, Viney
    Benjamin, Biju
    Dutta, Tathagata
    Velpandian, Thirumurthy
    Khar, Roop Krishen
    [J]. AAPS PHARMSCITECH, 2011, 12 (02): : 712 - 722
  • [26] Development of Lipid-Based Nanoparticles for Enhancing the Oral Bioavailability of Paclitaxel
    Deepti Pandita
    Alka Ahuja
    Viney Lather
    Biju Benjamin
    Tathagata Dutta
    Thirumurthy Velpandian
    Roop Krishen Khar
    [J]. AAPS PharmSciTech, 2011, 12 : 712 - 722
  • [27] Methods Used for Enhancing the Bioavailability of Oral Curcumin in Randomized Controlled Trials: A Meta-Research Study
    Mimica, Bruna
    Popovic, Viljemka Bucevic
    Banjari, Ines
    Kadic, Antonia Jelicic
    Puljak, Livia
    [J]. PHARMACEUTICALS, 2022, 15 (08)
  • [28] Lipid/Clay-Based Solid Dispersion Formulation for Improving the Oral Bioavailability of Curcumin
    Song, Jae Geun
    Noh, Hye-Mi
    Lee, Sang Hoon
    Han, Hyo-Kyung
    [J]. PHARMACEUTICS, 2022, 14 (11)
  • [29] A combination of complexation and self-nanoemulsifying drug delivery system for enhancing oral bioavailability and anticancer efficacy of curcumin
    Shukla, Mahendra
    Jaiswal, Swati
    Sharma, Abhisheak
    Srivastava, Pradeep Kumar
    Arya, Abhishek
    Dwivedi, Anil Kumar
    Lal, Jawahar
    [J]. DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY, 2017, 43 (05) : 847 - 861
  • [30] Nanotechnology Based Approaches for Enhancing Oral Bioavailability of Poorly Water Soluble Antihypertensive Drugs
    Sharma, Mayank
    Sharma, Rajesh
    Jain, Dinesh Kumar
    [J]. SCIENTIFICA, 2016, 2016