Two new monoterpene esters from Illigera paviflora Dunn roots

被引：2
|
作者：
Jiang, Meng-Yuan [1 ,2 ]
Pu, Xiao-Yun [1 ,2 ]
Li, Wen-Ting [3 ]
Liu, Juan [1 ,2 ]
Zeng, Xiao-Li [1 ,2 ]
Li, Hong-Rui [1 ,2 ]
Bai, Xi-Shan [1 ,2 ]
Hu, Lin [1 ,2 ]
Huang, Xiang-Zhong [1 ,2 ]
机构：
[1] Yunnan Minzu Univ, Key Lab Chem Ethn Med Resources, State Ethn Affairs Commiss, Kunming, Yunnan, Peoples R China
[2] Yunnan Minzu Univ, Minist Educ, Kunming, Yunnan, Peoples R China
[3] Kunming Ctr Dis Control & Prevent, Kunming, Yunnan, Peoples R China
来源：
NATURAL PRODUCT RESEARCH | 2024年 / 38卷 / 07期
基金：
中国国家自然科学基金;
关键词：
Illigera paviflora Dunn; monoterpene; aporphine alkaloid; anti-inflammatory activity; alpha-glucosidase inhibition; APORPHINE ALKALOIDS; CONSTITUENTS; LUZONENSIS;
D O I：
10.1080/14786419.2022.2137802
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
Two new monoterpene esters, illigerates H and I (1 and 2), and six known compounds actinodaphine (3), bulbocupnine (4), stephanine (5), hypserpanine B (6), betulinic acid (7) and gallic acid (8) were obtained from the root of Illigera paviflora Dunn. Their structures were elucidated by spectroscopic analysis. Anti-inflammatory and alpha-glucosidase inhibitory activity of some isolated compounds were assessed. Two monoterpenes 1 and 2 exhibited weak in vitro anti-inflammatory activity (IC50 64.5 +/- 5.3 and 79.2 +/- 7.5 mu M) while compounds 3-6 showed inhibition of alpha-glucosidase with IC50 values ranged from 87.17 to 118.74 mu M. [GRAPHICS]
引用
收藏
页码：1230 / 1237
页数：8
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