A Phase I Study of Ex Vivo Expanded Allogeneic Bone Marrow Derived Mesenchymal Stem Cells for the Treatment of Pediatric Perianal Fistulizing Crohn's Disease

被引：0
|
作者：
Pineiro, A. Otero [1 ]
Lightner, A. L. [1 ]
Reese, J. [2 ]
Ream, J. [3 ]
Nachand, D. [3 ]
Adams, A. [4 ]
VanDenBossche, A. [1 ]
Kurowski, J. [5 ]
机构：
[1] Cleveland Clin, Colorectal Surg, Digest Dis Surg Inst, Cleveland, OH USA
[2] Cleveland Clin, Natl Ctr Regenerat Med, Cleveland, OH USA
[3] Cleveland Clin, Dept Abdominal Radiol, Digest Dis Surg Inst, Cleveland, OH USA
[4] Cleveland Clin, Dept Colorectal Surg, Digest Dis Surg Inst, Cleveland, OH USA
[5] Cleveland Clin, Pediat, Pediat Inst, Cleveland, OH USA
来源：
JOURNAL OF CROHNS & COLITIS | 2023年 / 17卷
关键词：
D O I：
暂无
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
P718
引用
收藏
页码：848 / 848
页数：1
相关论文
共 50 条
  • [41] A phase III randomised controlled trial of Cx601, expanded allogeneic adipose-derived mesenchymal stem cells (eASC), for complex perianal fistulas in Crohn's disease
    Panes, J.
    Garcia-Olmo, D.
    Van Assche, G.
    Colombel, J. F.
    Reinisch, W.
    Baumgart, D. C.
    Nachury, M.
    Ferrante, M.
    Kazemi-Shirazi, L.
    Grimaud, J. C.
    de la Portilla, F.
    Goldin, E.
    Leselbaum, A.
    Diez, M. C.
    Danese, S.
    JOURNAL OF CROHNS & COLITIS, 2016, 10 : S1 - S1
  • [42] The role of children's bone marrow mesenchymal stromal cells in the ex vivo expansion of autologous and allogeneic hematopoietic stem cells
    Pelagiadis, Iordanis
    Stiakaki, Eftichia
    Choulaki, Christianna
    Kalmanti, Maria
    Dimitriou, Helen
    CELL BIOLOGY INTERNATIONAL, 2015, 39 (10) : 1099 - 1110
  • [43] Mesenchymal Stem Cells Versus Placebo for Perianal Fistulizing Crohn's Disease: A Systemic Review and Meta-Analysis
    Li, Ang
    Liu, Sailiang
    Li, Laiyuan
    Yu, Minhao
    SURGICAL INNOVATION, 2023, 30 (03) : 398 - 405
  • [44] Safety of Bone marrow-derived Allogeneic Mesenchymal Stem Cells in Parkinson's Disease Patients
    Schiess, M.
    Suescun, J.
    Ellmore, T.
    Doursout, M. F.
    Furr-Stimming, E.
    Mei, Z.
    Gee, A.
    MOVEMENT DISORDERS, 2019, 34 : S82 - S84
  • [45] Study of oncogenic transformation in ex vivo expanded mesenchymal cells, from paediatric bone marrow
    Choumerianou, D. M.
    Dimitriou, H.
    Perdikogianni, C.
    Martimianaki, G.
    Riminucci, M.
    Kalmanti, M.
    CELL PROLIFERATION, 2008, 41 (06) : 909 - 922
  • [46] Strategies to retain properties of bone marrow-derived mesenchymal stem cells ex vivo
    Zhou, Yaxian
    Tsai, Tsung-Lin
    Li, Wan-Ju
    ANNALS OF THE NEW YORK ACADEMY OF SCIENCES, 2017, 1409 (01) : 3 - 17
  • [47] A Phase IB/IIA Study of Allogeneic, Bone Marrow-derived, Mesenchymal Stem Cells for the Treatment of Refractory Ileal-anal Anastomosis and Peripouch Fistulas in the Setting of Crohn's Disease of the Pouch
    Lightner, Amy L.
    Reese, Jane
    Ream, Justin
    Nachand, Douglas
    Jia, Xue
    Pineiro, Ana Otero
    Dadgar, Neda
    Steele, Scott
    Hull, Tracy
    JOURNAL OF CROHNS & COLITIS, 2022, : 480 - 488
  • [48] Adult allogenic bone marrow-derived mesenchymal stem cells for the treatment of rectovaginal fistulas in the setting of Crohn's disease
    Otero-Pineiro, A. M.
    Lightner, A. L.
    TECHNIQUES IN COLOPROCTOLOGY, 2022, 26 (10) : 831 - 832
  • [49] Adult allogenic bone marrow-derived mesenchymal stem cells for the treatment of rectovaginal fistulas in the setting of Crohn’s disease
    A. M. Otero-Piñeiro
    A. L. Lightner
    Techniques in Coloproctology, 2022, 26 : 831 - 832
  • [50] Autologous bone marrow-derived mesenchymal stromal cell treatment for refractory luminal Crohn's disease: results of a phase I study
    Duijvestein, Marjolijn
    Vos, Anne Christine W.
    Roelofs, Helene
    Wildenberg, Manon E.
    Wendrich, Barbara B.
    Verspaget, Henricus W.
    Kooy-Winkelaar, Engelina M. C.
    Koning, Frits
    Zwaginga, Jaap Jan
    Fidder, Herma H.
    Verhaar, Auke P.
    Fibbe, Willem E.
    van den Brink, Gijs R.
    Hommes, Daniel W.
    GUT, 2010, 59 (12) : 1662 - 1669
12345