Expectant management of patent ductus arteriosus for preterm infants: A meta-analysis of randomized controlled trials

被引：5

作者：

Cheema, Huzaifa Ahmad ^{[1
,2
]}

Majeed, Zuhair ^{[1
]}

Hayat, Tajamal ^{[1
]}

Ahmed, Arslan ^{[2
]}

Tariq, Muhammad Haider ^{[2
]}

Shahid, Abia ^{[1
]}

Titus, Anoop ^{[3
]}

Minhas, Abdul Mannan Khan ^{[4
]}

Ijaz, Sardar Hassan ^{[5
]}

Ghelani, Sunil J. ^{[6
,7
]}

Kulkarni, Aparna ^{[8
]}

Dani, Sourbha S. ^{[5
]}

机构：

[1] King Edward Med Univ, Dept Cardiol, Lahore 54000, Punjab, Pakistan

[2] King Edward Med Univ, Dept Med, Lahore, Pakistan

[3] St Vincent Hosp, Dept Internal Med, Worcester, MA USA

[4] Univ Mississippi, Med Ctr, Dept Med, Jackson, MS USA

[5] Lahey Hosp & Med Ctr, Beth Israel Lahey Hlth, Div Cardiovasc Med, Burlington, MA USA

[6] Boston Childrens Hosp, Dept Cardiol, Boston, MA USA

[7] Harvard Med Sch, Dept Pediat, Boston, MA USA

[8] Donald & Barbara Zucker Sch Med, Childrens Heart Ctr, Cohen Childrens Med Ctr Northwell Hlth, New York, NY USA

来源：

AMERICAN HEART JOURNAL | 2023年 / 266卷

关键词：

D O I：

10.1016/j.ahj.2023.07.007

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We conducted this meta-analysis to compare expectant management of patent ductus arteriosus (PDA) with active treatment for PDA closure in preterm infants. Data from 7 randomized controlled trials (RCTs) showed that all-cause mortality and other clinical adverse outcomes did not differ between expectant management of PDA and active treatment. Future large-scale and double-blinded RCTs with a consistent definition for hemodynamically significant PDA, and focusing on clearly delineated high-risk subgroups or later selective treatment are needed to further evaluate the role of expectant management. (Am Heart J 2023;266:179-183.)

引用

页码：179 / 183

页数：5

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