Cytomegalovirus immunoglobulin therapy for CMV retinitis post hematopoietic stem cell transplantation

被引：1
|
作者：
Chiu, Tzu-Yu [1 ,2 ]
Huang, Min-Yu [1 ]
Wu, Horng-Jiun [1 ,2 ]
机构：
[1] Kaohsiung Med Univ, Kaohsiung Med Univ Hosp, Dept Ophthalmol, Kaohsiung, Taiwan
[2] Kaohsiung Med Univ, Coll Med, Sch Med, Kaohsiung, Taiwan
来源：
EUROPEAN JOURNAL OF OPHTHALMOLOGY | 2023年 / 33卷 / 04期
关键词：
CMV retinitis; cytomegalovirus immunoglobulin; hematopoietic stem cell transplantation; RISK-FACTORS;
D O I：
10.1177/11206721221112802
中图分类号：
R77 [眼科学];
学科分类号：
100212 ;
摘要：
Purpose To report a case of cytomegalovirus (CMV) retinitis complicated with ganciclovir-related myelosuppression, which was successfully managed with intravenous (IV) ganciclovir and CMV immunoglobulin (CMVIG) therapy. Methods Observational case report. Results A 51-year-old male with follicular type non-Hodgkin lymphoma post hematopoietic stem cell transplantation (HSCT) developed vision-threatening retinitis. polymerase chain reaction (PCR) of the aqueous humour showed positive for CMV. Despite myelosuppression occurred during IV ganciclovir therapy, the retinitis resolved and intraocular CMV viral load significantly improved after CMVIG therapy. Conclusion Combined IV ganciclovir treatment and CMVIG therapy can significantly improve visual outcome and reduce intraocular CMV viral load in vision-threatening CMV retinitis.
引用
收藏
页码：NP101 / NP104
页数：4
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