共 50 条
- [1] Rewired proteostasis in KRAS inhibitor resistanceNature Reviews Drug Discovery, 2023, 22 : 871 - 871Alex Eccleston论文数: 0 引用数: 0 h-index: 0
- [2] Decoding the proteostasis network in resistance to KRAS inhibitorsINNOVATION, 2023, 4 (06):Song, Xinxin论文数: 0 引用数: 0 h-index: 0机构: Univ Texas Southwestern Med Ctr, Dept Surg, Dallas, TX 75390 USA Univ Texas Southwestern Med Ctr, Dept Surg, Dallas, TX 75390 USAZhou, Zhuan论文数: 0 引用数: 0 h-index: 0机构: Univ Texas Southwestern Med Ctr, Dept Surg, Dallas, TX 75390 USA Univ Texas Southwestern Med Ctr, Dept Surg, Dallas, TX 75390 USAWestover, Kenneth D.论文数: 0 引用数: 0 h-index: 0机构: Univ Texas Southwestern Med Ctr, Dept Radiat Oncol & Biochem, Dallas, TX 75390 USA Univ Texas Southwestern Med Ctr, Dept Surg, Dallas, TX 75390 USA
- [3] Addicted to proteostasis: How KRAS-driven cancers acquire resistance to clinical KRAS inhibitorsCELL CHEMICAL BIOLOGY, 2023, 30 (11) : 1334 - 1336Klein, Austin T.论文数: 0 引用数: 0 h-index: 0机构: Northwestern Univ, Feinberg Sch Med, Dept Biochem & Mol Genet, Chicago, IL 60611 USA Northwestern Univ, Simpson Querrey Ctr Epigenet, Feinberg Sch Med, Chicago, IL 60611 USA Northwestern Univ, Robert H Lurie Comprehens Canc Ctr, Feinberg Sch Med, Chicago, IL 60611 USA Northwestern Univ, Feinberg Sch Med, Dept Biochem & Mol Genet, Chicago, IL 60611 USAMendillo, Marc L.论文数: 0 引用数: 0 h-index: 0机构: Northwestern Univ, Feinberg Sch Med, Dept Biochem & Mol Genet, Chicago, IL 60611 USA Northwestern Univ, Simpson Querrey Ctr Epigenet, Feinberg Sch Med, Chicago, IL 60611 USA Northwestern Univ, Robert H Lurie Comprehens Canc Ctr, Feinberg Sch Med, Chicago, IL 60611 USA Northwestern Univ, Feinberg Sch Med, Dept Biochem & Mol Genet, Chicago, IL 60611 USA
- [4] Modulation of the proteostasis network promotes tumor resistance to oncogenic KRAS inhibitorsSCIENCE, 2023, 381 (6662) : 1065 - +Lv, Xiangdong论文数: 0 引用数: 0 h-index: 0机构: Baylor Coll Med, Dept Mol & Cellular Biol, Houston, TX 77030 USA Baylor Coll Med, Lester & Sue Smith Breast Ctr, Houston, TX 77030 USA Baylor Coll Med, Dan L Duncan Comprehens Canc Ctr, Houston, TX 77030 USA Baylor Coll Med, Dept Mol & Cellular Biol, Houston, TX 77030 USALu, Xuan论文数: 0 引用数: 0 h-index: 0机构: Baylor Coll Med, Dept Mol & Cellular Biol, Houston, TX 77030 USA Baylor Coll Med, Lester & Sue Smith Breast Ctr, Houston, TX 77030 USA Baylor Coll Med, Dan L Duncan Comprehens Canc Ctr, Houston, TX 77030 USA Baylor Coll Med, Dept Mol & Cellular Biol, Houston, TX 77030 USACao, Jin论文数: 0 引用数: 0 h-index: 0机构: Baylor Coll Med, Dept Mol & Cellular Biol, Houston, TX 77030 USA Baylor Coll Med, Lester & Sue Smith Breast Ctr, Houston, TX 77030 USA Baylor Coll Med, Dan L Duncan Comprehens Canc Ctr, Houston, TX 77030 USA Baylor Coll Med, Dept Mol & Cellular Biol, Houston, TX 77030 USALuo, Qin论文数: 0 引用数: 0 h-index: 0机构: Baylor Coll Med, Dept Mol & Cellular Biol, Houston, TX 77030 USA Baylor Coll Med, Lester & Sue Smith Breast Ctr, Houston, TX 77030 USA Baylor Coll Med, Dan L Duncan Comprehens Canc Ctr, Houston, TX 77030 USA Baylor Coll Med, Dept Mol & Cellular Biol, Houston, TX 77030 USADing, Yao论文数: 0 引用数: 0 h-index: 0机构: Baylor Coll Med, Dept Mol & Cellular Biol, Houston, TX 77030 USA Baylor Coll Med, Lester & Sue Smith Breast Ctr, Houston, TX 77030 USA Baylor Coll Med, Dan L Duncan Comprehens Canc Ctr, Houston, TX 77030 USA Baylor Coll Med, Dept Mol & Cellular Biol, Houston, TX 77030 USAPeng, Fanglue论文数: 0 引用数: 0 h-index: 0机构: Baylor Coll Med, Dept Mol & Cellular Biol, Houston, TX 77030 USA Baylor Coll Med, Lester & Sue Smith Breast Ctr, Houston, TX 77030 USA Baylor Coll Med, Dan L Duncan Comprehens Canc Ctr, Houston, TX 77030 USA Baylor Coll Med, Dept Mol & Cellular Biol, Houston, TX 77030 USAPataer, Apar论文数: 0 引用数: 0 h-index: 0机构: Univ Texas MD Anderson Canc Ctr, Dept Thorac & Cardiovasc Surg, Houston, TX 77030 USA Baylor Coll Med, Dept Mol & Cellular Biol, Houston, TX 77030 USALu, Dong论文数: 0 引用数: 0 h-index: 0机构: Baylor Coll Med, Dept Mol & Cellular Biol, Houston, TX 77030 USA Baylor Coll Med, Dept Pharmacol & Chem Biol, Houston, TX 77030 USA Baylor Coll Med, Ctr Drug Discovery, Houston, TX 77030 USA Baylor Coll Med, Dept Mol & Cellular Biol, Houston, TX 77030 USAHan, Dong论文数: 0 引用数: 0 h-index: 0机构: Baylor Coll Med, Dept Mol & Cellular Biol, Houston, TX 77030 USA Baylor Coll Med, Lester & Sue Smith Breast Ctr, Houston, TX 77030 USA Baylor Coll Med, Dan L Duncan Comprehens Canc Ctr, Houston, TX 77030 USA Baylor Coll Med, Dept Mol & Cellular Biol, Houston, TX 77030 USAMalmberg, Eric论文数: 0 引用数: 0 h-index: 0机构: Baylor Coll Med, Dept Mol & Cellular Biol, Houston, TX 77030 USA Baylor Coll Med, Lester & Sue Smith Breast Ctr, Houston, TX 77030 USA Baylor Coll Med, Dan L Duncan Comprehens Canc Ctr, Houston, TX 77030 USA Baylor Coll Med, Dept Mol & Cellular Biol, Houston, TX 77030 USAChan, Doug W.论文数: 0 引用数: 0 h-index: 0机构: Baylor Coll Med, Dept Mol & Cellular Biol, Houston, TX 77030 USA Baylor Coll Med, Lester & Sue Smith Breast Ctr, Houston, TX 77030 USA Baylor Coll Med, Dan L Duncan Comprehens Canc Ctr, Houston, TX 77030 USA Baylor Coll Med, Dept Mol & Cellular Biol, Houston, TX 77030 USAWang, Xiaoran论文数: 0 引用数: 0 h-index: 0机构: Baylor Coll Med, Dept Mol & Cellular Biol, Houston, TX 77030 USA Baylor Coll Med, Lester & Sue Smith Breast Ctr, Houston, TX 77030 USA Baylor Coll Med, Dan L Duncan Comprehens Canc Ctr, Houston, TX 77030 USA Baylor Coll Med, Dept Mol & Cellular Biol, Houston, TX 77030 USASavage, Sara R.论文数: 0 引用数: 0 h-index: 0机构: Baylor Coll Med, Lester & Sue Smith Breast Ctr, Houston, TX 77030 USA Baylor Coll Med, Dan L Duncan Comprehens Canc Ctr, Houston, TX 77030 USA Baylor Coll Med, Dept Mol & Human Genet, Houston, TX 77030 USA Baylor Coll Med, Dept Mol & Cellular Biol, Houston, TX 77030 USAMao, Sufeng论文数: 0 引用数: 0 h-index: 0机构: Baylor Coll Med, Dept Mol & Cellular Biol, Houston, TX 77030 USA Baylor Coll Med, Lester & Sue Smith Breast Ctr, Houston, TX 77030 USA Baylor Coll Med, Dan L Duncan Comprehens Canc Ctr, Houston, TX 77030 USA Baylor Coll Med, Dept Mol & Cellular Biol, Houston, TX 77030 USAYu, Jingjing论文数: 0 引用数: 0 h-index: 0机构: Baylor Coll Med, Dept Mol & Cellular Biol, Houston, TX 77030 USA Baylor Coll Med, Lester & Sue Smith Breast Ctr, Houston, TX 77030 USA Baylor Coll Med, Dan L Duncan Comprehens Canc Ctr, Houston, TX 77030 USA Baylor Coll Med, Dept Mol & Cellular Biol, Houston, TX 77030 USAPeng, Fei论文数: 0 引用数: 0 h-index: 0机构: Baylor Coll Med, Dept Mol & Cellular Biol, Houston, TX 77030 USA Baylor Coll Med, Div Diabet Endocrinol & Metab, Dept Med, Houston, TX 77030 USA Baylor Coll Med, Dept Mol & Cellular Biol, Houston, TX 77030 USAYan, Liang论文数: 0 引用数: 0 h-index: 0机构: Univ Texas MD Anderson Canc Ctr, Dept Mol & Cellular Oncol, Houston, TX 77030 USA Baylor Coll Med, Dept Mol & Cellular Biol, Houston, TX 77030 USAMeng, Huan论文数: 0 引用数: 0 h-index: 0机构: Baylor Coll Med, Dept Mol & Cellular Biol, Houston, TX 77030 USA Baylor Coll Med, Dept Mol & Cellular Biol, Houston, TX 77030 USAManeix, Laure论文数: 0 引用数: 0 h-index: 0机构: Baylor Coll Med, Dept Mol & Cellular Biol, Houston, TX 77030 USA Baylor Coll Med, Huffington Ctr Aging, Houston, TX USA Baylor Coll Med, Dept Mol & Cellular Biol, Houston, TX 77030 USAHan, Yumin论文数: 0 引用数: 0 h-index: 0机构: Baylor Coll Med, Dept Mol & Cellular Biol, Houston, TX 77030 USA Baylor Coll Med, Lester & Sue Smith Breast Ctr, Houston, TX 77030 USA Baylor Coll Med, Dan L Duncan Comprehens Canc Ctr, Houston, TX 77030 USA Baylor Coll Med, Dept Mol & Cellular Biol, Houston, TX 77030 USAChen, Yiwen论文数: 0 引用数: 0 h-index: 0机构: Univ Texas MD Anderson Canc Ctr, Dept Bioinformat & Computat Biol, Houston, TX 77030 USA Baylor Coll Med, Dept Mol & Cellular Biol, Houston, TX 77030 USAYao, Wantong论文数: 0 引用数: 0 h-index: 0机构: Univ Texas MD Anderson Canc Ctr, Dept Translat Mol Pathol, Houston, TX 77030 USA Baylor Coll Med, Dept Mol & Cellular Biol, Houston, TX 77030 USAChang, Eric C.论文数: 0 引用数: 0 h-index: 0机构: Baylor Coll Med, Dept Mol & Cellular Biol, Houston, TX 77030 USA Baylor Coll Med, Lester & Sue Smith Breast Ctr, Houston, TX 77030 USA Baylor Coll Med, Dan L Duncan Comprehens Canc Ctr, Houston, TX 77030 USA Baylor Coll Med, Dept Mol & Cellular Biol, Houston, TX 77030 USACatic, Andre论文数: 0 引用数: 0 h-index: 0机构: Baylor Coll Med, Dept Mol & Cellular Biol, Houston, TX 77030 USA Baylor Coll Med, Huffington Ctr Aging, Houston, TX USA Baylor Coll Med, Dept Mol & Cellular Biol, Houston, TX 77030 USALin, Xia论文数: 0 引用数: 0 h-index: 0机构: Baylor Coll Med, Div Surg Oncol, Michael E DeBakey Dept Surg, Houston, TX 77030 USA Baylor Coll Med, Dept Mol & Cellular Biol, Houston, TX 77030 USAMiles, George论文数: 0 引用数: 0 h-index: 0机构: Baylor Coll Med, Lester & Sue Smith Breast Ctr, Houston, TX 77030 USA Baylor Coll Med, Dan L Duncan Comprehens Canc Ctr, Houston, TX 77030 USA Baylor Coll Med, Dept Mol & Human Genet, Houston, TX 77030 USA Baylor Coll Med, Dept Mol & Cellular Biol, Houston, TX 77030 USAHuang, Pengxiang论文数: 0 引用数: 0 h-index: 0机构: Baylor Coll Med, Dept Mol & Cellular Biol, Houston, TX 77030 USA Baylor Coll Med, Dept Mol & Cellular Biol, Houston, TX 77030 USASun, Zheng论文数: 0 引用数: 0 h-index: 0机构: Baylor Coll Med, Dept Mol & Cellular Biol, Houston, TX 77030 USA Baylor Coll Med, Div Diabet Endocrinol & Metab, Dept Med, Houston, TX 77030 USA Baylor Coll Med, Dept Mol & Cellular Biol, Houston, TX 77030 USABurt, Bryan论文数: 0 引用数: 0 h-index: 0机构: Baylor Coll Med, Div Thorac Surg, Michael E DeBakey Dept Surg, Houston, TX 77030 USA Baylor Coll Med, Dept Mol & Cellular Biol, Houston, TX 77030 USAWang, Huamin论文数: 0 引用数: 0 h-index: 0机构: Univ Texas MD Anderson Canc Ctr, Dept Pathol, Houston, TX 77030 USA Baylor Coll Med, Dept Mol & Cellular Biol, Houston, TX 77030 USAWang, Jin论文数: 0 引用数: 0 h-index: 0机构: Baylor Coll Med, Dept Mol & Cellular Biol, Houston, TX 77030 USA Baylor Coll Med, Dept Pharmacol & Chem Biol, Houston, TX 77030 USA Baylor Coll Med, Ctr Drug Discovery, Houston, TX 77030 USA Baylor Coll Med, Dept Mol & Cellular Biol, Houston, TX 77030 USAYao, Qizhi Cathy论文数: 0 引用数: 0 h-index: 0机构: Baylor Coll Med, Div Surg Oncol, Michael E DeBakey Dept Surg, Houston, TX 77030 USA Baylor Coll Med, Dept Mol & Cellular Biol, Houston, TX 77030 USAZhang, Bing论文数: 0 引用数: 0 h-index: 0机构: Baylor Coll Med, Lester & Sue Smith Breast Ctr, Houston, TX 77030 USA Baylor Coll Med, Dan L Duncan Comprehens Canc Ctr, Houston, TX 77030 USA Baylor Coll Med, Dept Mol & Human Genet, Houston, TX 77030 USA Baylor Coll Med, Dept Mol & Cellular Biol, Houston, TX 77030 USARoth, Jack A.论文数: 0 引用数: 0 h-index: 0机构: Univ Texas MD Anderson Canc Ctr, Dept Thorac & Cardiovasc Surg, Houston, TX 77030 USA Baylor Coll Med, Dept Mol & Cellular Biol, Houston, TX 77030 USAO'Malley, Bert W.论文数: 0 引用数: 0 h-index: 0机构: Baylor Coll Med, Dept Mol & Cellular Biol, Houston, TX 77030 USA Baylor Coll Med, Dept Mol & Cellular Biol, Houston, TX 77030 USAEllis, Matthew J.论文数: 0 引用数: 0 h-index: 0机构: Baylor Coll Med, Lester & Sue Smith Breast Ctr, Houston, TX 77030 USA Baylor Coll Med, Dan L Duncan Comprehens Canc Ctr, Houston, TX 77030 USA AstraZeneca, Early Oncol, Oncol R&D, Gaithersburg, MD USA Baylor Coll Med, Dept Mol & Cellular Biol, Houston, TX 77030 USARimawi, Mothaffar F.论文数: 0 引用数: 0 h-index: 0机构: Baylor Coll Med, Lester & Sue Smith Breast Ctr, Houston, TX 77030 USA Baylor Coll Med, Dan L Duncan Comprehens Canc Ctr, Houston, TX 77030 USA Baylor Coll Med, Dept Mol & Cellular Biol, Houston, TX 77030 USAYing, Haoqiang论文数: 0 引用数: 0 h-index: 0机构: Univ Texas MD Anderson Canc Ctr, Dept Mol & Cellular Oncol, Houston, TX 77030 USA Baylor Coll Med, Dept Mol & Cellular Biol, Houston, TX 77030 USAChen, Xi论文数: 0 引用数: 0 h-index: 0机构: Baylor Coll Med, Dept Mol & Cellular Biol, Houston, TX 77030 USA Baylor Coll Med, Lester & Sue Smith Breast Ctr, Houston, TX 77030 USA Baylor Coll Med, Dan L Duncan Comprehens Canc Ctr, Houston, TX 77030 USA Baylor Coll Med, Dept Mol & Cellular Biol, Houston, TX 77030 USA
- [5] Mechanisms of KRAS Inhibitor Resistance RevealedCANCER DISCOVERY, 2021, 11 (06) : 1311 - 1312Caruso, Catherine论文数: 0 引用数: 0 h-index: 0
- [6] KRAS: Biology, Inhibition, and Mechanisms of Inhibitor ResistanceCURRENT ONCOLOGY, 2024, 31 (04) : 2024 - 2046Ash, Leonard J.论文数: 0 引用数: 0 h-index: 0机构: CUNY, Hunter Coll, Dept Biol Sci, New York, NY 10065 USA CUNY, Grad Ctr, Mol Cellular & Dev Biol Subprogram Biol Ph D Progr, New York, NY 10031 USA CUNY, Hunter Coll, Dept Biol Sci, New York, NY 10065 USABusia-Bourdain, Ottavia论文数: 0 引用数: 0 h-index: 0机构: CUNY, Hunter Coll, Dept Biol Sci, New York, NY 10065 USA CUNY, Hunter Coll, Dept Biol Sci, New York, NY 10065 USAOkpattah, Daniel论文数: 0 引用数: 0 h-index: 0机构: CUNY, Grad Ctr, Biochem Ph D Program, New York, NY 10031 USA CUNY, Hunter Coll, Dept Biol Sci, New York, NY 10065 USAKamel, Avrosina论文数: 0 引用数: 0 h-index: 0机构: CUNY, Hunter Coll, Dept Biol Sci, New York, NY 10065 USA CUNY, Macaulay Honors Coll, Hunter Coll, New York, NY 10065 USA CUNY, Hunter Coll, Dept Biol Sci, New York, NY 10065 USALiberchuk, Ariel论文数: 0 引用数: 0 h-index: 0机构: CUNY, Hunter Coll, Dept Biol Sci, New York, NY 10065 USA CUNY, Macaulay Honors Coll, Hunter Coll, New York, NY 10065 USA CUNY, Hunter Coll, Dept Biol Sci, New York, NY 10065 USAWolfe, Andrew L.论文数: 0 引用数: 0 h-index: 0机构: CUNY, Hunter Coll, Dept Biol Sci, New York, NY 10065 USA CUNY, Grad Ctr, Mol Cellular & Dev Biol Subprogram Biol Ph D Progr, New York, NY 10031 USA CUNY, Grad Ctr, Biochem Ph D Program, New York, NY 10031 USA Weill Cornell Med, Dept Pharmacol, New York, NY 10021 USA CUNY, Hunter Coll, Dept Biol Sci, New York, NY 10065 USA
- [7] SOS1 inhibitor combinations overcome KRAS inhibitor resistanceNATURE CANCER, 2024, 5 (09) : 1294 - 1295Hofmann, Marco H.论文数: 0 引用数: 0 h-index: 0机构: Boehringer Ingelheim GmbH & Co KG, Vienna, Austria Boehringer Ingelheim GmbH & Co KG, Vienna, AustriaJurado, Sabine论文数: 0 引用数: 0 h-index: 0机构: Boehringer Ingelheim GmbH & Co KG, Vienna, Austria Boehringer Ingelheim GmbH & Co KG, Vienna, Austria
- [8] Targeting KRAS inhibitor resistance by ferroptosis induction in PDACCANCER RESEARCH, 2024, 84 (17)Padhye, Aparna论文数: 0 引用数: 0 h-index: 0Yu, Qijia论文数: 0 引用数: 0 h-index: 0Sindoni, Nicole论文数: 0 引用数: 0 h-index: 0Zhang, Huan论文数: 0 引用数: 0 h-index: 0Dilly, Julien论文数: 0 引用数: 0 h-index: 0Feng, Hanrong论文数: 0 引用数: 0 h-index: 0Aguirre, Andrew论文数: 0 引用数: 0 h-index: 0Mancias, Joseph论文数: 0 引用数: 0 h-index: 0
- [9] Intrinsic resistance mechanisms to mutant KRAS specific inhibitor in KRAS mutated colorectal cancerCANCER SCIENCE, 2023, 114 : 1210 - 1210Maruyama, Kohei论文数: 0 引用数: 0 h-index: 0机构: JFCR, Div Exp Chemother, Canc Chemother Ctr, Tokyo, Japan Univ Tokyo, Grad Sch Front Sci, Dept CBMS, Tokyo, Japan JFCR, Div Exp Chemother, Canc Chemother Ctr, Tokyo, JapanSuzuki, Mai论文数: 0 引用数: 0 h-index: 0机构: JFCR, Div Exp Chemother, Canc Chemother Ctr, Tokyo, Japan Univ Tokyo, Grad Sch Front Sci, Dept CBMS, Tokyo, Japan JFCR, Div Exp Chemother, Canc Chemother Ctr, Tokyo, JapanOhhara, Tomoko论文数: 0 引用数: 0 h-index: 0机构: JFCR, Div Exp Chemother, Canc Chemother Ctr, Tokyo, Japan JFCR, Div Exp Chemother, Canc Chemother Ctr, Tokyo, JapanNagayama, Satoshi论文数: 0 引用数: 0 h-index: 0机构: JFCR, Canc Inst Hosp, Dept Gastroenterol Surg, Tokyo, Japan JFCR, Div Exp Chemother, Canc Chemother Ctr, Tokyo, JapanFujita, Naoya论文数: 0 引用数: 0 h-index: 0机构: JFCR, Canc Chemother Ctr, Tokyo, Japan JFCR, Div Exp Chemother, Canc Chemother Ctr, Tokyo, JapanKatayama, Ryohei论文数: 0 引用数: 0 h-index: 0机构: JFCR, Div Exp Chemother, Canc Chemother Ctr, Tokyo, Japan Univ Tokyo, Grad Sch Front Sci, Dept CBMS, Tokyo, Japan JFCR, Div Exp Chemother, Canc Chemother Ctr, Tokyo, Japan
- [10] Intrinsic resistance mechanisms to mutant KRAS specific inhibitor in KRAS mutated colorectal cancerCANCER SCIENCE, 2023, 114 : 783 - 783Maruyama, Kohei论文数: 0 引用数: 0 h-index: 0机构: JFCR, Div Exp Chemother, Canc Chemother Ctr, Tokyo, Japan Univ Tokyo, Dept CBMS, Grad Sch Front Sci, Tokyo, Japan JFCR, Div Exp Chemother, Canc Chemother Ctr, Tokyo, JapanSuzuki, Mai论文数: 0 引用数: 0 h-index: 0机构: JFCR, Div Exp Chemother, Canc Chemother Ctr, Tokyo, Japan Univ Tokyo, Dept CBMS, Grad Sch Front Sci, Tokyo, Japan JFCR, Div Exp Chemother, Canc Chemother Ctr, Tokyo, JapanOhhara, Tomoko论文数: 0 引用数: 0 h-index: 0机构: JFCR, Div Exp Chemother, Canc Chemother Ctr, Tokyo, Japan JFCR, Div Exp Chemother, Canc Chemother Ctr, Tokyo, JapanNagayama, Satoshi论文数: 0 引用数: 0 h-index: 0机构: JFCR, Canc Inst Hosp, Dept Surg Gastroenterol, Tokyo, Japan JFCR, Div Exp Chemother, Canc Chemother Ctr, Tokyo, JapanFujita, Naoya论文数: 0 引用数: 0 h-index: 0机构: JFCR, Canc Chemother Ctr, Tokyo, Japan JFCR, Div Exp Chemother, Canc Chemother Ctr, Tokyo, JapanKatayama, Ryohei论文数: 0 引用数: 0 h-index: 0机构: JFCR, Div Exp Chemother, Canc Chemother Ctr, Tokyo, Japan Univ Tokyo, Dept CBMS, Grad Sch Front Sci, Tokyo, Japan JFCR, Div Exp Chemother, Canc Chemother Ctr, Tokyo, Japan