Organs-on-chips: a decade of innovation

被引：10

作者：

Strelez, Carly ^{[1
]}

Jiang, Hannah Y. ^{[1
,2
]}

Mumenthaler, Shannon M. ^{[1
,2
,3
]}

机构：

[1] Lawrence J Ellison Inst Transformat Med, Los Angeles, CA 90064 USA

[2] Univ Southern Calif, Viterbi Sch Engn, Dept Biomed Engn, Los Angeles, CA 90089 USA

[3] Univ Southern Calif, Norris Comprehens Canc Ctr, Keck Sch Med, Dept Oncol, Los Angeles, CA 90033 USA

来源：

TRENDS IN BIOTECHNOLOGY | 2023年 / 41卷 / 03期

关键词：

DEVICES;

D O I：

10.1016/j.tibtech.2023.01.004

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Recreating 'living organs' with groundbreaking organ-on-a-chip (OOC) technologies is facilitating a new era of drug discovery. Studies by Huh et al. and Ronaldson-Bouchard et al. underscore advances made over a decade, spanning single organ functionality to interconnected organs, that enable examination of drug toxicities and disease pathogenesis in reconstituted tissues.

引用

页码：278 / 280

页数：3

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