Aggressive fluid management may be associated with disease progression in suspected sepsis patients admitted to the intensive care unit: a retrospective cohort study

Sepsis is a lethal condition characterized by multiple organ dysfunction due to disrupted host responses to severe infections.[1] Affected patients often have a Sequential Organ Failure Assessment (SOFA) score >= 2.[2] Patients with a SOFA score < 2 and at least one of the following were considered as "suspected sepsis": (1) quick SOFA (qSOFA) score >= 2; (2) SOFA score = 1; or (3) National Early Warning Score (NEWS) 4-6.[3] Compared with studies on fluid resuscitation in sepsis patients, there are few studies on fluid management in patients with suspected sepsis. Therefore, we conducted a retrospective cohort study to evaluate the relationship between fluid management and disease progression in suspected sepsis patients.