Comparison of Preoperative Measurement Methods of Alveolar Cleft Volume Using Cone Beam Computed Tomography between Computer Simulation and Water Displacement Methods

Objective To compare the use of a computer simulation by Mimics software and the water displacement method as means for measurement of alveolar cleft volume on cone beam computed tomography (CBCT) data. Design Prospective study. Settling Institutional research. Patients Patients with unilateral complete cleft lip and palate (UCCLP) who would undergo alveolar bone grafting. Interventions CBCT images of twenty patients with UCCLP were included in the study. In the first method, the water displacement method was adopted to measure volume of plasticine filled in the alveolar cleft imprinted on 3D printed model of maxilla. In the second method a volumetric assessment function in Mimics software was adopted to measure volume of 3D virtual model of alveolar cleft constructed from CBCT images. A comparison on the alveolar cleft volumes derived from the two methods was assessed using the statistical paired t-test. Main Outcome Measure The paired-t test showed no statistically significant difference between alveolar cleft volumes measured by the two methods (P = 0.075). Results Mean volume of the alveolar cleft measured by the water displacement method was 1.03 +/- 0.31 ml whereas by the computer simulation using Mimics software the value was 1.00 +/- 0.31 ml. The mean difference between the two methods was 0.03 +/- 0.08 ml. Conclusion The computer simulation by Mimics software as a means for measurement of alveolar cleft volume on CBCT data is as accurate as the measurement by the water displacement method.