Predictive role of pretreatment skeletal muscle mass index for long-term survival of bladder cancer patients: A meta-analysis

被引:1
|
作者
Yuan, Qian [1 ,2 ]
Hu, Jianrong [1 ,2 ]
Yuan, Feng [1 ,2 ]
An, Jingjing [1 ,2 ]
机构
[1] Sichuan Univ, West China Hosp, Dept Anesthesiol, Chengdu, Peoples R China
[2] Sichuan Univ, West China Sch Nursing, Chengdu, Sichuan, Peoples R China
来源
PLOS ONE | 2023年 / 18卷 / 06期
关键词
RADICAL CYSTECTOMY; NUTRITIONAL-STATUS; SARCOPENIA; DISEASE; IMPACT; RISK;
D O I
10.1371/journal.pone.0288077
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
PurposeTo identify the predictive role of pretreatment skeletal muscle mass index (SMI) for long-term survival of bladder cancer patients. MethodsSeveral databases were searched for studies investigating the relationship between pretreatment SMI and prognosis in bladder cancer. The overall survival (OS) and cancer-specific survival (CSS) were defined as primary and secondary outcomes, respectively. Hazard ratios (HRs) and 95% confidence intervals (CIs) were combined. ResultsNine studies involving 1476 cases were included. The results demonstrated that a lower pretreatment SMI was significantly related to poorer OS (HR = 1.56, 95% CI: 1.33-1.82, P<0.001) and subgroup analysis based on thresholds of SMI revealed similar results. Besides, pretreatment SMI was also obviously related to CSS (HR = 1.75, 95% CI: 1.36-2.25, P<0.001). ConclusionLower pretreatment SMI was associated with worse long-term survival of bladder cancer patients.
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页数:11
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