Features of Clinical Complexity in European Patients With Atrial Fibrillation: A Report From a European Observational Prospective AF Registry

被引：14

作者：

Proietti, Marco ^{[1
,2
,3
,4
]}

Romiti, Giulio F. ^{[1
,2
,5
]}

Corica, Bernadette ^{[1
,2
,5
]}

Mei, Davide A. ^{[1
,2
]}

Bonini, Niccolo ^{[1
,2
,6
,7
]}

Vitolo, Marco ^{[1
,2
,6
,7
]}

Imberti, Jacopo F. ^{[1
,2
,6
,7
]}

Boriani, Giuseppe ^{[6
]}

Lip, Gregory Y. H. ^{[1
,2
,8
,9
]}

机构：

[1] Liverpool John Moores Univ, Liverpool Ctr Cardiovasc Sci, Univ Liverpool, Liverpool, England

[2] Liverpool Heart & Chest Hosp, Liverpool, England

[3] Univ Milan, Dept Clin Sci & Community Hlth, Milan, Italy

[4] IRCCS Ist Clin Sci Maugeri, Div Subacute Care, Milan, Italy

[5] Sapienza Univ Rome, Dept Translat & Precis Med, Rome, Italy

[6] Univ Modena & Reggio Emilia, Dept Biomed Metab & Neural Sci, Cardiol Div, Policlin Modena, Modena, Italy

[7] Univ Modena & Reggio Emilia, Clin & Expt Med PhD Program, Modena, Italy

[8] Aalborg Univ, Danish Ctr Clin Hlth Serv Res, Dept Clin Med, Aalborg, Denmark

[9] Univ Liverpool, Liverpool Ctr Cardiovasc Sci, William Henry Duncan Bldg,6 West Derby St, Liverpool L7 8TX, England

来源：

CURRENT PROBLEMS IN CARDIOLOGY | 2023年 / 48卷 / 08期

关键词：

DISEASE;

D O I：

10.1016/j.cpcardiol.2023.101752

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

There is increasing concern regarding impact of clinical complexity in patients with atrial fibrillation (AF). We explored the impact of different clinical complexity features in AF patients. We ana-lyzed patients from a prospective, observational, mul-ticenter Europe-wide AF registry. Features of clinical complexity among patients with CHA2DS2-VASc >2 were: (1) history of bleeding; (2) frailty; (3) chronic kidney disease (CKD); (4) >2 features. A total of 10,169 patients were analyzed. Of these, 141 (1.4%) had history of bleeding, 954 (9.4%) were frail, 1767 (17.4%) had CKD and 1253 (12.3%) had >2 features. All features of clinical complexity were less treated with OAC. History of bleeding (HR 1.94, 95% CI 1.32-2.85), frailty (HR 1.38, 95% CI 1.11-1.71), CKD (HR 1.50, 95% 1.28-1.75) and >2 features (HR 2.08, 95% CI 1.73-2.51) were associated with outcomes. Presence of features of clinical complexity is associated with lower use of OAC and higher risk of outcomes. (Curr Probl Cardiol 2023;48:101752.)

引用

页数：21

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