PSMA PET/CT Versus mpMRI for the Detection of Clinically Significant Prostate Cancer: An Updated Overview

被引：6
|
作者：
Caracciolo, Matteo [1 ]
Castello, Angelo [2 ]
Lopci, Egesta [3 ,4 ]
机构：
[1] Univ Hosp Ferrara, Oncol Med & Specialists Dept, Nucl Med Unit, Ferrara, Italy
[2] Fdn IRCCS CaGranda, Osped Maggiore Policlin, Nucl Med Unit, Milan, Italy
[3] IRCCS, Human Res Hosp, Nucl Med Unit, Milan, Italy
[4] IRCCS, Human Res Hosp, Nucl Med Unit, Via Manzoni 56, I-20089 Milan, Italy
来源：
SEMINARS IN NUCLEAR MEDICINE | 2024年 / 54卷 / 01期
关键词：
GA-68-PSMA PET/CT; DIAGNOSTIC-ACCURACY; BIOPSY; VALIDATION; MRI; PSA;
D O I：
10.1053/j.semnuclmed.2023.10.002
中图分类号：
R8 [特种医学]; R445 [影像诊断学];
学科分类号：
1002 ; 100207 ; 1009 ;
摘要：
In the last years, PSMA-PET imaging and multiparametric MRI (mpMRI) have improved the clinical management of prostate cancer (PCa) patients. Currently, mpMRI is recommended by the EAU (European Association of Urology) guidelines for the primary diagnosis of PCa, whereas PSMA-PET is reserved for disease staging, particularly in high risk localized or locally advanced disease, as well as for biochemical recurrence after surgery. Nevertheless, several studies have explored the added value of PSMA-PET in other clinical scenar-ios, including primary diagnosis and especially for the detection of clinically significant PCa (csPCa). In the present contribution, we will provide an overview and an update on the cur-rent literature on imaging detection of csPCa, with a particular focus on mpMRI, PSMA-PET and their comparison. Semin Nucl Med 54:30-38 (c) 2023 Elsevier Inc. All rights reserved.
引用
收藏
页码：30 / 38
页数：9
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