Outcome of elexacaftor/tezacaftor/ivacaftor therapy in patients with cystic fibrosis and solid organ transplantation

被引：7
|
作者：
Orum, Matilde B. [1 ,8 ]
Ronsholt, Frederikke F. [2 ,3 ]
Jeppesen, Majbritt [1 ,4 ]
Bendstrup, Elisabeth [4 ,5 ]
Katzenstein, Terese L. [3 ]
Ott, Peter [4 ,6 ]
Perch, Michael [2 ,7 ]
Pressler, Tacjana [3 ]
Qvist, Tavs [3 ]
Jensen-Fangel, Soren [4 ]
机构：
[1] Aarhus Univ Hosp, Dept Infect Dis, Cyst Fibrosis Clin, Aarhus, Denmark
[2] Univ Hosp Rigshospitalet Copenhagen, Dept Cardiol, Sect Lung Transplantat, Copenhagen, Denmark
[3] Univ Hosp Rigshospitalet Copenhagen, Dept Infect Dis, Cyst Fibrosis Clin, Copenhagen, Denmark
[4] Aarhus Univ, Inst Clin Med, Aarhus, Denmark
[5] Aarhus Univ Hosp, Ctr Rare Lung Dis, Dept Resp Dis & Allergy, Aarhus, Denmark
[6] Aarhus Univ Hosp, Dept Hepatol & Gastroenterol, Aarhus, Denmark
[7] Univ Copenhagen, Dept Clin Med, Copenhagen, Denmark
[8] Aarhus Univ Hosp, Dept Infect Dis, Cyst Fibrosis Clin, Palle Juul Jensens Blvd 99, DK-8200 Aarhus N, Denmark
来源：
PEDIATRIC PULMONOLOGY | 2023年 / 58卷 / 02期
关键词：
CFTR therapy; cystic fibrosis; cystic fibrosis transmembrane conductance regulator therapy; ETI; solid organ transplantation;
D O I：
10.1002/ppul.26217
中图分类号：
R72 [儿科学];
学科分类号：
100202 ;
摘要：
We report a case series of four patients with cystic fibrosis (CF) and previous solid organ transplantation (SOT) receiving elexacaftor/tezacaftor/ivacaftor therapy for 6 months or more. Data was collected retrospectively. The treatment was well tolerated and all patients reported subjective improvements.
引用
收藏
页码：602 / 605
页数：4
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