Outcome of elexacaftor/tezacaftor/ivacaftor therapy in patients with cystic fibrosis and solid organ transplantation

被引：7

作者：

Orum, Matilde B. ^{[1
,8
]}

Ronsholt, Frederikke F. ^{[2
,3
]}

Jeppesen, Majbritt ^{[1
,4
]}

Bendstrup, Elisabeth ^{[4
,5
]}

Katzenstein, Terese L. ^{[3
]}

Ott, Peter ^{[4
,6
]}

Perch, Michael ^{[2
,7
]}

Pressler, Tacjana ^{[3
]}

Qvist, Tavs ^{[3
]}

Jensen-Fangel, Soren ^{[4
]}

机构：

[1] Aarhus Univ Hosp, Dept Infect Dis, Cyst Fibrosis Clin, Aarhus, Denmark

[2] Univ Hosp Rigshospitalet Copenhagen, Dept Cardiol, Sect Lung Transplantat, Copenhagen, Denmark

[3] Univ Hosp Rigshospitalet Copenhagen, Dept Infect Dis, Cyst Fibrosis Clin, Copenhagen, Denmark

[4] Aarhus Univ, Inst Clin Med, Aarhus, Denmark

[5] Aarhus Univ Hosp, Ctr Rare Lung Dis, Dept Resp Dis & Allergy, Aarhus, Denmark

[6] Aarhus Univ Hosp, Dept Hepatol & Gastroenterol, Aarhus, Denmark

[7] Univ Copenhagen, Dept Clin Med, Copenhagen, Denmark

[8] Aarhus Univ Hosp, Dept Infect Dis, Cyst Fibrosis Clin, Palle Juul Jensens Blvd 99, DK-8200 Aarhus N, Denmark

来源：

PEDIATRIC PULMONOLOGY | 2023年 / 58卷 / 02期

关键词：

CFTR therapy; cystic fibrosis; cystic fibrosis transmembrane conductance regulator therapy; ETI; solid organ transplantation;

D O I：

10.1002/ppul.26217

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

We report a case series of four patients with cystic fibrosis (CF) and previous solid organ transplantation (SOT) receiving elexacaftor/tezacaftor/ivacaftor therapy for 6 months or more. Data was collected retrospectively. The treatment was well tolerated and all patients reported subjective improvements.

引用

页码：602 / 605

页数：4

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