Prospective screening for monkeypox infection among users of HIV pre-exposure prophylaxis in Denmark

被引:2
|
作者
Thomassen, Sofie Ellen [1 ]
von Schreeb, Sebastian [1 ,2 ]
Kirkby, Nikolai Soren [3 ]
Pinholt, Mette [4 ]
Lebech, Anne-Mette [5 ,6 ]
Kronborg, Gitte [1 ,6 ]
Engsig, Frederik Neess [1 ]
机构
[1] Copenhagen Univ Hosp Amager & Hvidovre, Dept Infect Dis, Copenhagen, Denmark
[2] Statens Serum Inst, Infect Dis Epidemiol & Prevent, Copenhagen, Denmark
[3] Copenhagen Univ Hosp, Rigshospitalet, Dept Clin Microbiol, Copenhagen, Denmark
[4] Copenhagen Univ Hosp Amager & Hvidovre, Dept Clin Microbiol, Copenhagen, Denmark
[5] Copenhagen Univ Hosp, Rigshospitalet, Dept Infect Dis, Copenhagen, Denmark
[6] Univ Copenhagen, Fac Hlth & Med Sci, Copenhagen, Denmark
关键词
Monkeypox; screening; asymptomatic; pre-exposure prophylaxis; HIV pre-exposure prophylaxis; vaccine; vaccination;
D O I
10.1177/09564624231223764
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Introduction: During the 2022 outbreak of mpox (previously called monkeypox), which primarily affected Gay, Bisexual, and other Men who have Sex with Men (GBMSM), testing was mainly limited to individuals with symptoms of infection. Although sporadic cases of mpox continue to be diagnosed in Denmark, the feasibility of screening asymptomatic high-risk populations, such as those using HIV pre-exposure prophylaxis (PrEP), is still unknown. Methods: During the autumn of 2022, a rectal swab test for mpox PCR was included in the routine sexually transmitted infections (STI) screening for PrEP users. Results: The screening included 224 asymptomatic men with a median age of 36.5 years. One patient (0.4%) tested positive for mpox. Ten (4.5%) and nine (4.0%) had chlamydia and gonorrhea, respectively. Discussion: Our study demonstrates that screening for mpox is feasible in two Danish PrEP clinics.
引用
收藏
页码:374 / 378
页数:5
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