Glucose-dependent insulin production and insulin-independence in patients with type 1 diabetes infused with stem cell-derived, fully differentiated islet cells (VX-880)

被引：0
|
作者：
Reichman, T. [1 ]
Ricordi, C. [2 ]
Naji, A. [3 ]
Markmann, J. F. [4 ]
Perkins, B. [5 ]
Bruinsma, B. G. [6 ]
Marigowda, G. [6 ]
Melton, D. [6 ]
Pagliuca, F. [6 ]
Sanna, B. [6 ]
Kean, L. S. [7 ,8 ]
Mathieu, C. [9 ]
Peters, A. [10 ]
Witkowski, P. [11 ]
Rickels, M. R. [3 ]
机构：
[1] Toronto Gen Hosp, Toronto, ON, Canada
[2] Univ Miami, Miami, FL USA
[3] Univ Penn Perlman, Sch Med, Philadelphia, PA USA
[4] Massachusetts Gen Hosp, Boston, MA USA
[5] Mt Sinai Hosp, Toronto, ON, Canada
[6] Vertex Pharmaceut Inc, Boston, MA USA
[7] Boston Childrens Hosp, Boston, MA USA
[8] Dana Farber Canc Inst, Boston, MA USA
[9] Katholieke Univ Leuven, Leuven, Belgium
[10] Univ Southern Calif, Los Angeles, CA USA
[11] Univ Chicago, Chicago, IL USA
来源：
DIABETOLOGIA | 2023年 / 66卷 / SUPPL 1期
关键词：
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
449
引用
收藏
页码：S229 / S230
页数：2
相关论文
共 50 条
  • [31] Human mesenchymal stem cell-derived microvesicles modulate T cell response to islet antigen glutamic acid decarboxylase in patients with type 1 diabetes
    Enrica Favaro
    Andrea Carpanetto
    Sara Lamorte
    Alberto Fusco
    Cristiana Caorsi
    Maria C. Deregibus
    Stefania Bruno
    Antonio Amoroso
    Mirella Giovarelli
    Massimo Porta
    Paolo Cavallo Perin
    Ciro Tetta
    Giovanni Camussi
    Maria M. Zanone
    Diabetologia, 2014, 57 : 1664 - 1673
  • [32] THE EFFECTS OF GLUCOSE-DEPENDENT INSULINOTROPIC POLYPEPTIDE INFUSED AT PHYSIOLOGICAL CONCENTRATIONS IN NORMAL SUBJECTS AND TYPE-2 (NON-INSULIN-DEPENDENT) DIABETIC-PATIENTS ON GLUCOSE-TOLERANCE AND B-CELL SECRETION
    JONES, IR
    OWENS, DR
    MOODY, AJ
    LUZIO, SD
    MORRIS, T
    HAYES, TM
    DIABETOLOGIA, 1987, 30 (09) : 707 - 712
  • [33] Co-microencapsulation of human umbilical cord-derived mesenchymal stem and pancreatic islet-derived insulin producing cells in experimental type 1 diabetes
    Montanucci, Pia
    Pescara, Teresa
    Greco, Alessia
    Leonardi, Giulia
    Marini, Luigi
    Basta, Giuseppe
    Calafiore, Riccardo
    DIABETES-METABOLISM RESEARCH AND REVIEWS, 2021, 37 (02)
  • [34] ISLET PEPTIDE SECRETION IN PATIENTS WITH TYPE-1 (INSULIN-DEPENDENT) PANCREATOGENIC DIABETES WITHOUT RESIDUAL B-CELL FUNCTION
    LARSEN, S
    HILSTED, J
    TRONIER, B
    WORNING, H
    DIABETOLOGIA, 1986, 29 (08) : A563 - A563
  • [35] Stem Cell-Derived Islet Replacement Therapy (VC-02) Demonstrates Production of C-Peptide in Patients with Type 1 Diabetes (T1D) and Hypoglycemia Unawareness
    Keymeulen, Bart
    Jacobs-Tulleneers-Thevissen, Daniel, Sr.
    Kroon, Evert J.
    Jaiman, Manasi S.
    Daniels, Mark
    Wang, Richard
    Pipeleers, Daniel
    D'Amour, Kevin
    Foyt, Howard L.
    DIABETES, 2021, 70
  • [36] HETEROGENEITY OF ISLET-CELL CYTOPLASMIC ANTIBODIES AND AUTOANTIBODIES TO GLUTAMATE-DECARBOXYLASE IN RELATIVES OF PATIENTS WITH TYPE-1 (INSULIN-DEPENDENT) DIABETES
    BERGEROT, I
    SOUCHIER, C
    THIVOLET, C
    COMPTES RENDUS DE L ACADEMIE DES SCIENCES SERIE III-SCIENCES DE LA VIE-LIFE SCIENCES, 1993, 316 (11): : 1368 - 1373
  • [37] Four weeks of near-normalisation of blood glucose improves the insulin response to glucagon-like peptide-1 and glucose-dependent insulinotropic polypeptide in patients with type 2 diabetes
    Hojberg, P. V.
    Vilsboll, T.
    Rabol, R.
    Knop, F. K.
    Bache, M.
    Krarup, T.
    Holst, J. J.
    Madsbad, S.
    DIABETOLOGIA, 2009, 52 (02) : 199 - 207
  • [38] Four weeks of near-normalisation of blood glucose improves the insulin response to glucagon-like peptide-1 and glucose-dependent insulinotropic polypeptide in patients with type 2 diabetes
    P. V. Højberg
    T. Vilsbøll
    R. Rabøl
    F. K. Knop
    M. Bache
    T. Krarup
    J. J. Holst
    S. Madsbad
    Diabetologia, 2009, 52
  • [39] ISLET-CELL ANTIBODIES AND INTRAVENOUS GLUCOSE-TOLERANCE TESTING IN 1ST DEGREE RELATIVES OF TYPE-1 (INSULIN-DEPENDENT) DIABETIC-PATIENTS - PROGRESSION TO INSULIN DEFICIENCY
    BECKER, F
    BUSCHLER, H
    SCHERER, S
    SAUER, H
    BRETZEL, R
    FEDERLIN, K
    DIABETOLOGIA, 1989, 32 (07) : A465 - A465
  • [40] Polymer Thin Film Device for Immuno-protective Encapsulation of Human Stem Cell Derived Insulin Producing Cells for the Treatment of Type 1 Diabetes
    Chang, R.
    Faleo, G.
    Russ, H.
    Hebrok, M.
    Tang, Q.
    Desai, T.
    TISSUE ENGINEERING PART A, 2016, 22 : S34 - S34
12345