A Machine Learning Method for Automated Description and Workflow Analysis of First Trimester Ultrasound Scans

被引:9
|
作者
Yasrab, Robail [1 ]
Fu, Zeyu [1 ]
Zhao, He [1 ]
Lee, Lok Hin [1 ]
Sharma, Harshita [1 ]
Drukker, Lior [2 ,3 ]
Papageorgiou, Aris T. [1 ,2 ]
Noble, J. Alison
机构
[1] Univ Oxford, Inst Biomed Engn, Oxford OX3 7DQ, England
[2] Univ Oxford, Dept Womens & Reprod Hlth, Oxford OX3 7DQ, England
[3] Tel Aviv Univ, Sackler Fac Med, Rabin Med Ctr, IL-6997801 Tel Aviv, Israel
基金
英国工程与自然科学研究理事会; 欧洲研究理事会;
关键词
Ultrasonic imaging; Streaming media; Standards; Annotations; Task analysis; Pregnancy; Ultrasonic variables measurement; First trimester; ultrasound; spatio-temporal analysis; video classification; clinical workflow; FETAL STRUCTURAL ANOMALIES; IMAGE SEGMENTATION;
D O I
10.1109/TMI.2022.3226274
中图分类号
TP39 [计算机的应用];
学科分类号
081203 ; 0835 ;
摘要
Obstetric ultrasound assessment of fetal anatomy in the first trimester of pregnancy is one of the less explored fields in obstetric sonography because of the paucity of guidelines on anatomical screening and availability of data. This paper, for the first time, examines imaging proficiency and practices of first trimester ultrasound scanning through analysis of full-length ultrasound video scans. Findings from this study provide insights to inform the development of more effective user-machine interfaces, of targeted assistive technologies, as well as improvements in workflow protocols for first trimester scanning. Specifically, this paper presents an automated framework to model operator clinical workflow from full-length routine first-trimester fetal ultrasound scan videos. The 2D+t convolutional neural network-based architecture proposed for video annotation incorporates transfer learning and spatio-temporal (2D+t) modelling to automatically partition an ultrasound video into semantically meaningful temporal segments based on the fetal anatomy detected in the video. The model results in a cross-validation A1 accuracy of 96.10% , F1=0.95 , precision =0.94 and recall =0.95 . Automated semantic partitioning of unlabelled video scans (n=250) achieves a high correlation with expert annotations ( ? = 0.95, p=0.06 ). Clinical workflow patterns, operator skill and its variability can be derived from the resulting representation using the detected anatomy labels, order, and distribution. It is shown that nuchal translucency (NT) is the toughest standard plane to acquire and most operators struggle to localize high-quality frames. Furthermore, it is found that newly qualified operators spend 25.56% more time on key biometry tasks than experienced operators.
引用
收藏
页码:1301 / 1313
页数:13
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