Gain or Amplification of Chromosome 1q Mediate Multiple Myeloma Resistant to Xpo-1 Inhibitor Selinexor Via Transcription Factor ETV3

被引：0

作者：

Gu, Huiyao ^{[1
]}

Zhong, Yi ^{[1
]}

Zhang, Enfan ^{[2
]}

Cao, Liqin ^{[3
]}

Cai, Zhen ^{[4
]}

He, Jingsong ^{[5
]}

机构：

[1] Zhejiang Univ, Sch Med, Affiliated Hosp 1, Bone Marrow Transplantat Ctr,Dept Hematol, Hangzhou, Peoples R China

[2] Zhejiang Univ, Sch Med, Affiliated Hosp 1, Bone Marrow Transplantat Ctr, Hangzhou, Peoples R China

[3] Zhejiang Univ, Sch Med, Affiliated Hosp 1, Hangzhou, Peoples R China

[4] Zhejiang Univ, Affiliated Hosp 1, Bone Marrow Transplantat Ctr, Sch Med, Hangzhou, Peoples R China

[5] Zhejiang Univ, Affiliated Hosp 1, Dept Bone Marrow Transplantat Ctr, Sch Med, Hangzhou, Peoples R China

来源：

BLOOD | 2023年 / 142卷

关键词：

ETV3; multiple myeloma; Gain or amplification of chromosome 1q; selinexor;

D O I：

10.1182/blood-2023-184720

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页数：3

共 39 条

[21] PROGNOSTIC IMPACT OF GAIN AND AMPLIFICATION OF 1Q IN NEWLY DIAGNOSED MULTIPLE MYELOMA PATIENTS RECEIVING CARFILZOMIB-BASED TREATMENT IN THE FORTE TRIAL
D'Agostino, M.
Rota-Scalabrini, D.
Corradini, P.
Ballanti, S.
Arigoni, M.
Giuliani, N.
Pietrantuono, G.
Olivero, M.
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Pisani, F.
Cafro, A. M.
Mussatto, C.
Vincelli, D.
Tosi, P.
Liberati, A. M.
Palmieri, S.
Aquino, S.
Calogero, R. A.
Grasso, M.
Cavo, M.
Musto, P.
Boccadoro, M.
Gay, F.
HAEMATOLOGICA, 2021, 106 (10) : 57 - 58
[22] IGF2BP1 promotes multiple myeloma with chromosome 1q gain via increasing CDC5L expression in an m6A-dependent manner
Xu, Jiadai
Wang, Yawen
Ren, Liang
Li, Panpan
Liu, Peng
GENES & DISEASES, 2025, 12 (01)
[23] Gain of chromosome 1q portends worse prognosis in multiple myeloma despite novel agent-based induction regimens and autologous transplantation
Shah, Gunjan L.
Landau, Heather
Londono, Dory
Devlin, Sean M.
Kosuri, Satyajit
Lesokhin, Alexander M.
Lendvai, Nikoletta
Hassoun, Hani
Chung, David J.
Koehne, Guenther
Jhanwar, Suresh C.
Landgren, Ola
Levine, Ross
Giralt, Sergio A.
LEUKEMIA & LYMPHOMA, 2017, 58 (08) : 1823 - 1831
[24] IGF2BP1 Promotes Multiple Myeloma with Chromosome 1q Gain Via Increasing CDC5L Expression in an m6A-Dependent Mannery
Xu, Jiadai
Liu, Peng
BLOOD, 2023, 142
[25] Adar-Mediated Aberrant a-to-I RNA Editing Is Driven By 1q Amplification and Contributes to Proteasome Inhibitor Resistance in Multiple Myeloma
Lagana, Alessandro
Leshchenko, Violetta
Melnekoff, David
Beno, Itai
Perumal, Deepak
Keats, Jonathan
DeRome, Mary
Yesil, Jennifer
Auclair, Daniel
Madduri, Deepu
Chari, Ajai
Cho, Hearn Jay
Barlogie, Bart
Jagannath, Sundar
Dudley, Joel
Parekh, Samir
BLOOD, 2017, 130
[26] Outcome of Multiple Myeloma with Chromosome 1q Gain and 1p Deletion after High-Dose Therapy and Autologous Hematopoietic Stem Cell Transplantation
Varma, Ankur
Saini, Neeraj Y.
Sui, Dawen
Milton, Denai R.
Hasan, Omar
Mukherjee, Akash
Bashir, Qaiser
Rondon, Gabriela
Srour, Samer A.
Popat, Uday
Hosing, Chitra
Nieto, Yago
Kebriaei, Partow
Alousi, Amin M.
Mehta, Rohtesh S.
Khouri, Issa F.
Weber, Donna M.
Thomas, Sheeba K.
Manasanch, Elisabet E.
Lee, Hans C.
Patel, Krina K.
Ciurea, Stefan O.
Shpall, Elizabeth J.
Orlowski, Robert Z.
Champlin, Richard E.
Qazilbash, Muzaffar H.
BLOOD, 2018, 132
[27] Outcomes of Patients with Multiple Myeloma and 1q Gain/Amplification Receiving Autologous Hematopoietic Stem Cell Transplant: The MD Anderson Cancer Center Experience
Pasvolsky, Oren
Ghanem, Sassine
Milton, Denai R.
Rauf, Mikael
Tanner, Mark R.
Bashir, Qaiser
Srour, Samer A.
Saini, Neeraj Y.
Lin, Paul
Ramdial, Jeremy
Nieto, Yago
Khan, Hina N.
Kebriaei, Partow
Lee, Hans C.
Patel, Krina K.
Thomas, Sheeba K.
Weber, Donna M.
Orlowski, Robert Z.
Shpall, Elizabeth J.
Champlin, Richard E.
Qazilbash, Muzaffar H.
BLOOD, 2023, 142
[28] Outcome of Multiple Myeloma with Chromosome 1q Gain and 1p Deletion after Autologous Hematopoietic Stem Cell Transplantation: Propensity Score Matched Analysis
Varma, Ankur
Sui, Dawen
Milton, Denai R.
Tang, Guilin
Saini, Neeraj
Hasan, Omar
Mukherjee, Akash
Joseph, Jacinth Joy
Bashir, Qaiser
Rondon, Gabriela
Srour, Samer
Popat, Uday R.
Hosing, Chitra M.
Nieto, Yago
Kebriaei, Partow
Alousi, Amin M.
Ahmed, Sairah
Mehta, Rohtesh
Khouri, Issa F.
Ahmed, Haris
Iyer, Swaminathan
Weber, Donna M.
Thomas, Sheeba K.
Manasanch, Elisabet
Lee, Hans C.
Patel, Krina
Ciurea, Stefan O.
Shpall, Elizabeth J.
Orlowski, Robert Z.
Champlin, Richard E.
Qazilbash, Muzaffar H.
BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION, 2020, 26 (04) : 665 - 671
[29] Outcomes of patients with multiple myeloma and 1q gain/amplification receiving autologous hematopoietic stem cell transplant: the MD Anderson cancer center experience
Pasvolsky, Oren
Ghanem, Sassine
Milton, Denai R.
Rauf, Mikael
Tanner, Mark R.
Bashir, Qaiser
Srour, Samer
Saini, Neeraj
Lin, Paul
Ramdial, Jeremy
Nieto, Yago
Tang, Guilin
Aljawai, Yosra
Khan, Hina N.
Kebriaei, Partow
Lee, Hans C.
Patel, Krina K.
Thomas, Sheeba K.
Weber, Donna M.
Orlowski, Robert Z.
Shpall, Elizabeth J.
Champlin, Richard E.
Qazilbash, Muzaffar H.
BLOOD CANCER JOURNAL, 2024, 14 (01)
[30] Outcomes of patients with multiple myeloma and 1q gain/amplification receiving autologous hematopoietic stem cell transplant: the MD Anderson cancer center experience
Oren Pasvolsky
Sassine Ghanem
Denái R. Milton
Mikael Rauf
Mark R. Tanner
Qaiser Bashir
Samer Srour
Neeraj Saini
Paul Lin
Jeremy Ramdial
Yago Nieto
Guilin Tang
Yosra Aljawai
Hina N. Khan
Partow Kebriaei
Hans C. Lee
Krina K. Patel
Sheeba K. Thomas
Donna M. Weber
Robert Z. Orlowski
Elizabeth J. Shpall
Richard E. Champlin
Muzaffar H. Qazilbash
Blood Cancer Journal, 14

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