L-Proline Catalyzed Organic Reactions via Microwave-Activation

In the past few years, using microwave power to heat and wield chemical reactions has become a gradually more popular subject in the scientific community. Microwave-supported organic synthesis is confirmed to be involved in rapidly synthesizing novel compounds with selectivity and enhanced biological activities. Microwave flash heating for chemical synthesis is a spectacular reduction in reaction times, high yield and purity of the products, etc. A catalysis field wherein small organic molecules like L-Proline efficiently and selectively catalyzes organic transformations. Microwave-assisted L-Proline catalyzed reactions are valuable tools for making different acyclic, heterocycles, and carbocyclic scaffolds that signify the main framework of most bioactive compounds. In synthetic organic chemistry, microwave irradiation speedily discarded the conventional heating methods in the world of multicomponent and step-wise synthetic chemistry. This review discusses only L-Proline Catalyzed Organic Reactions under microwave activation using modern organic transformations, including condensation, addition, asymmetric, multi-components, and other modular reactions.