Plasma biomarkers for brain injury in extracorporeal membrane oxygenation

被引:0
|
作者
Kapoor, Shrey [1 ,2 ,3 ,4 ]
Kolchinski, Anna [1 ,2 ,3 ,4 ]
Gusdon, Aaron M. [5 ]
Premraj, Lavienraj [6 ,7 ]
Cho, Sung-Min [1 ,2 ,3 ,4 ]
机构
[1] Johns Hopkins Univ, Sch Med, Dept Neurol, Div Neurosci Crit Care & Cardiac Surg, Baltimore, MD USA
[2] Johns Hopkins Univ, Sch Med, Dept Surg, Div Neurosci Crit Care & Cardiac Surg, Baltimore, MD USA
[3] Johns Hopkins Univ, Sch Med, Dept Anesthesiol, Div Neurosci Crit Care & Cardiac Surg, Baltimore, MD USA
[4] Johns Hopkins Univ, Sch Med, Dept Crit Care Med, Div Neurosci Crit Care & Cardiac Surg, Baltimore, MD USA
[5] Univ Texas Hlth Sci Ctr Houston, McGovern Sch Med, Div Neurocrit Care, Dept Neurosurg, Houston, TX USA
[6] Griffith Univ, Sch Med, Griffith, NSW, Australia
[7] Prince Charles Hosp, Crit Care Res Grp, Chermside, Qld, Australia
关键词
acute brain injury; biomarkers; extracorporeal membrane oxygenation; FIBRILLARY ACIDIC PROTEIN; CELL-FREE DNA; MITOCHONDRIAL-DNA; ONCOSTATIN M; SERUM; GFAP; TAU; PREDICT; DAMAGE; S100B;
D O I
10.4266/acc.2023.01368
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
Extracorporeal membrane oxygenation (ECMO) is a life-saving intervention for patients with refractory cardiorespiratory failure. Despite its benefits, ECMO carries a significant risk of neurological complications, including acute brain injury (ABI). Although standardized neuromonitoring and neurological care have been shown to improve early detection of ABI, the inability to perform neuroimaging in a timely manner is a major limitation in the accurate diagnosis of neurological complications. Therefore, blood-based biomarkers capable of detecting ongoing brain injury at the bedside are of great clinical significance. This review aims to provide a concise review of the current literature on plasma biomarkers for ABI in patients on ECMO support.
引用
收藏
页码:389 / 398
页数:10
相关论文
共 50 条
  • [41] Severity of brain injury following neonatal extracorporeal membrane oxygenation and outcome at age 5 years
    Glass, P
    Bulas, DI
    Wagner, AE
    Rajasingham, SR
    Civitello, LA
    Papero, PH
    Coffman, CE
    Short, BL
    DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY, 1997, 39 (07): : 441 - 448
  • [42] Extracorporeal membrane oxygenation ameliorate hepatic injury in brain death rat donors with hemodynamic instability
    Yang, Jianbao
    Li, Jian
    Zhuoga, Awang
    Yu, Zeyuan
    Li, Yongnan
    Jiao, Zuoyi
    INTERNATIONAL JOURNAL OF ARTIFICIAL ORGANS, 2024, 47 (11): : 836 - 846
  • [43] The History of Extracorporeal Membrane Oxygenation and the Development of Extracorporeal Membrane Oxygenation Anticoagulation
    Bartlett, Robert
    Arachichilage, Deepa J.
    Chitlur, Meera
    Hui, Shiu-Ki Rocky
    Neunert, Cindy
    Doyle, Andrew
    Retter, Andrew
    Hunt, Beverley J.
    Lim, Hoong Sern
    Saini, Arun
    Renne, Thomas
    Kostousov, Vadim
    Teruya, Jun
    SEMINARS IN THROMBOSIS AND HEMOSTASIS, 2024, 50 (01): : 81 - 90
  • [44] Neural Networks to Predict Radiographic Brain Injury in Pediatric Patients Treated with Extracorporeal Membrane Oxygenation
    Shah, Neel
    Farhat, Abdelaziz
    Tweed, Jefferson
    Wang, Ziheng
    Lee, Jeon
    McBeth, Rafe
    Skinner, Michael
    Tian, Fenghua
    Thiagarajan, Ravi
    Raman, Lakshmi
    JOURNAL OF CLINICAL MEDICINE, 2020, 9 (09) : 1 - 14
  • [45] Pulse Pressure and Acute Brain Injury in Venoarterial Extracorporeal Membrane Oxygenation: An Extracorporeal Life Support Organization Registry Analysis
    Kalra, Andrew
    Kang, Jin Kook
    Wilcox, Christopher
    Shou, Benjamin L.
    Brown, Patricia
    Rycus, Peter
    Anders, Marc M.
    Zaaqoq, Akram M.
    Brodie, Daniel
    Whitman, Glenn J. R.
    Cho, Sung-Min
    HERALD Grp
    ASAIO JOURNAL, 2025, 71 (02) : 99 - 108
  • [46] Transcranial Doppler microemboli and acute brain injury in extracorporeal membrane oxygenation: A prospective observational study
    Caturegli, Giorgio
    Kapoor, Shrey
    Ponomarev, Vladimir
    Kim, Bo Soo
    Whitman, Glenn J. R.
    Ziai, Wendy
    Cho, Sung-Min
    JTCVS TECHNIQUES, 2022, 15 : 111 - 122
  • [47] Glial fibrillary acidic protein as a brain injury biomarker in children undergoing extracorporeal membrane oxygenation
    Bembea, Melania M.
    Savage, William
    Strouse, John J.
    Schwartz, Jamie McElrath
    Graham, Ernest
    Thompson, Carol B.
    Everett, Allen
    PEDIATRIC CRITICAL CARE MEDICINE, 2011, 12 (05) : 572 - 579
  • [48] EXTRACORPOREAL MEMBRANE OXYGENATION
    BRANTIGAN, CO
    GROW, JB
    ROCKY MOUNTAIN MEDICAL JOURNAL, 1978, 75 (02): : 97 - 103
  • [49] Extracorporeal membrane oxygenation
    Robert H. Bartlett
    Indian Journal of Thoracic and Cardiovascular Surgery, 2021, 37 : 196 - 197
  • [50] Extracorporeal membrane oxygenation
    Caron, EA
    Berlandi, JLH
    NURSING CLINICS OF NORTH AMERICA, 1997, 32 (01) : 125 - &