Inhibition of RAS signaling and tumorigenesis through targeting novel vulnerabilities

被引:0
|
作者
Kahn, Imran [1 ]
Koide, Akiko [2 ]
Zuberi, Mariyam [1 ]
Ketavarapu, Gayatri [2 ]
Denbaum, Eric [2 ]
Teng, Kai Wen [2 ]
Rhett, J. Matthew [1 ]
Spencer-Smith, Russell [3 ]
Hobbs, G. Aaron [1 ]
Camp, Earnest Ramsay [1 ]
Koide, Shohei [2 ]
O'Bryan, John P. [1 ]
机构
[1] Med Univ South Carolina, Charleston, SC USA
[2] NYU, Perlmutter Canc Ctr, Langone Hlth, New York, NY USA
[3] Univ Illinois, Chicago, IL USA
关键词
D O I
10.1158/1557-3125.RAS18-B01
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
B023
引用
收藏
页数:2
相关论文
共 50 条
  • [21] Inhibition of RAS-mediated transformation and tumorigenesis by targeting the downstream E3 ubiquitin ligase SIAH
    Tang, Amy
    Schmidt, Rebecca
    Park, Cheol
    Ahmed, Atique
    Gundelach, Justin
    Reed, Nanette
    Knudsen, Bruce
    Tang, Amy
    CANCER RESEARCH, 2008, 68 (09)
  • [22] Suppression of triple-negative breast cancer tumorigenesis by targeting cancer stem cells through JNK/Notch1 signaling inhibition
    Xie, Xuemei
    Kaoud, Tamer S.
    Edupunganti, Ramakrishna
    Zhang, Tinghu
    Kogawa, Takahiro
    Chauhan, Gaurav B.
    Giannoukos, Dionysios N.
    Qi, Yuan
    Tripathy, Debu
    Gray, Nathanael S.
    Dalby, Kevin N.
    Bartholomeusz, Chandra
    Ueno, Naoto T.
    CANCER RESEARCH, 2015, 75
  • [23] Targeting hyperactive Ras signaling in acute leukemia
    Shannon, Kevin M.
    CANCER RESEARCH, 2016, 76
  • [24] Targeting Ras/ERK signaling in the striatum: will it help?
    R Brambilla
    Molecular Psychiatry, 2003, 8 : 366 - 368
  • [25] Targeting oncogenic Ras signaling in hematologic malignancies
    Ward, Ashley F.
    Braun, Benjamin S.
    Shannon, Kevin M.
    BLOOD, 2012, 120 (17) : 3397 - 3406
  • [26] Targeting Ras/ERK signaling in the striatum: will it help?
    Brambilla, R
    MOLECULAR PSYCHIATRY, 2003, 8 (04) : 366 - 368
  • [27] Regulation of a novel human phospholipase C, PLCε, through membrane targeting by Ras
    Song, C
    Hu, CD
    Masago, M
    Kariya, K
    Yamawaki-Kataoka, Y
    Shibatohge, M
    Wu, DM
    Satoh, T
    Kataoka, T
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2001, 276 (04) : 2752 - 2757
  • [28] Inhibition of ITGA2 suppresses cervical tumorigenesis and metastasis by targeting the AKT/mTOR signaling pathway
    Luo, Haixia
    Chang, Jingjing
    Ren, Yiting
    Zhang, Xiu
    Li, Yuanxing
    Huo, Miao
    Wang, Hongyuan
    Yang, Xin
    Liu, Jianbing
    Zhang, Qingmei
    Zhao, Yueyang
    Wang, Wei
    GENES & DISEASES, 2025, 12 (02)
  • [29] Inhibition of colorectal cancer tumorigenesis by ursolic acid and doxorubicin is mediated by targeting the Akt signaling pathway and activating the Hippo signaling pathway
    Hu, Dan
    Meng, Ruo Yu
    Nguyen, Thi Van
    Chai, Ok Hee
    Park, Byung Hyun
    Lee, Ju-Seog
    Kim, Soo Mi
    MOLECULAR MEDICINE REPORTS, 2023, 27 (01)
  • [30] Inhibition of Ras phenylation: A signaling target for novel anti-cancer drug design
    Lerner, EC
    Hamilton, AD
    Sebti, SM
    ANTI-CANCER DRUG DESIGN, 1997, 12 (04): : 229 - 238