Not if but when nanopore protein sequencing meets single-cell proteomics

被引：11

作者：

Motone, Keisuke ^{[1
]}

Nivala, Jeff ^{[1
,2
]}

机构：

[1] Univ Washington, Paul G Allen Sch Comp Sci & Engn, Seattle, WA 98195 USA

[2] Univ Washington, Mol Engn & Sci Inst, Seattle, WA 98195 USA

来源：

NATURE METHODS | 2023年 / 20卷 / 03期

关键词：

D O I：

10.1038/s41592-023-01800-7

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

The nanopore community is stepping toward a new frontier of single-molecule protein sequencing. Here, we offer our opinions on the unique potential for this emerging technology, with a focus on single-cell proteomics, and some challenges that must be overcome to realize it.

引用

页码：336 / 338

页数：3

共 50 条

[21] Single-cell proteomics.
Eberwine, J
Miyashiro, K
Kacharmina, JE
[J]. BIOLOGY OF REPRODUCTION, 2002, 66 : 70 - 70
[22] A dream of single-cell proteomics
Vivien Marx
[J]. Nature Methods, 2019, 16 : 809 - 812
[23] The rise of single-cell proteomics
Ctortecka, Claudia
Mechtler, Karl
[J]. ANALYTICAL SCIENCE ADVANCES, 2021, 2 (3-4): : 84 - 94
[24] Single-Cell Proteomics Is in the Chips
Marusina, Kate
[J]. Genetic Engineering and Biotechnology News, 2015, 35 (13): : 14 - 15
[25] Single-cell sequencing
Nawy, Tal
[J]. NATURE METHODS, 2014, 11 (01) : 18 - 18
[26] Single-cell sequencing
不详
[J]. Nature Biotechnology, 2022, 40 (3) : 303 - 303
[27] Single-cell sequencing
Tal Nawy
[J]. Nature Methods, 2014, 11 : 18 - 18
[28] Protein Adsorption Loss-The Bottleneck of Single-Cell Proteomics
Sun, Bingyun
Kumar, Sharwan
[J]. JOURNAL OF PROTEOME RESEARCH, 2022, 21 (08) : 1808 - 1815
[29] Single-cell sequencing
[J]. Nature, 2013, 493 (7431) : 136 - 136
[30] Proximity sequencing for single-cell measurement of protein complexes
[J]. Nature Methods, 2022, 19 : 1528 - 1529

← 1 2 3 4 5 →