Esophageal Neuroendocrine Carcinoma Presenting After Definitive Chemoradiation of Squamous Cell Carcinoma in the Same Location

被引：0
|
作者：
Prenatt, Zarian [1 ]
Liaquat, Hammad [2 ]
Shupp, Brittney [1 ]
Stoll, Lisa [3 ]
Schneider, Yecheskel [2 ]
机构：
[1] St Lukes Univ Hlth Network, Dept Internal Med, Bethlehem, PA 18014 USA
[2] St Lukes Univ Hlth Network, Dept Gastroenterol, Bethlehem, PA USA
[3] St Lukes Univ Hlth Network, Dept Pathol, Bethlehem, PA USA
来源：
ACG CASE REPORTS JOURNAL | 2023年 / 10卷 / 06期
关键词：
esophagus; esophageal neuroendocrine carcinoma; squamous cell carcinoma; radiation-induced malignancy; chemoradiation; MALIGNANCIES; RADIOTHERAPY; TUMOR; RISK;
D O I：
10.14309/crj.0000000000001091
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
Esophageal neuroendocrine carcinoma is very rare and highly aggressive. An 85-year-old man with a history of esophageal squamous cell carcinoma in remission presented 4 years after definitive chemoradiation with new-onset dysphagia. Endoscopy with biopsy revealed high-grade malignancy consistent with neuroendocrine carcinoma. Treatment options were limited to chemotherapy because of his metastatic disease, and he unfortunately died 14 months after diagnosis. The occurrence of esophageal neuroendocrine carcinoma in a site of prior squamous cell carcinoma is very uncommon, and this likely represents a case of radiation-induced malignancy. Therefore, when undergoing radiotherapy, patients and providers should discuss the possibility of this life-threatening complication.
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页数：4
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