Case report: Successful treatment with tofacitinib and colchicine in a patient with Schnitzler syndrome

被引：4

作者：

Li, Man ^{[1
]}

Chen, Yu-Wen ^{[2
]}

Shen, Amy ^{[3
]}

Xie, Yong-Xin ^{[1
]}

Wu, Yonglan ^{[1
]}

Zeng, Xianlin ^{[1
]}

Leong, Pui-Ying ^{[4
,5
,6
]}

机构：

[1] Second Hosp Longyan, Dept Rheumatol, Longyan, Peoples R China

[2] Taichung Vet Gen Hosp, Dept Dermatol, Taichung, Taiwan

[3] Univ Calif Los Angeles, David Geffen Sch Med, Los Angeles, CA 90095 USA

[4] Chung Shan Med Univ Hosp, Dept Internal Med, Div Allergy Immunol & Rheumatol, Taichung, Taiwan

[5] Chung Shan Med Univ, Inst Med, Taichung, Taiwan

[6] Chung Shan Med Univ, Sch Med, Taichung, Taiwan

来源：

INTERNATIONAL JOURNAL OF RHEUMATIC DISEASES | 2023年 / 26卷 / 01期

关键词：

anti-IL1 and anti-IL6; JAK inhibitors; Schnitzler syndrome;

D O I：

10.1111/1756-185X.14457

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We report a case of late-onset Schnitzler syndrome successfully treated with Janus-activated kinase (JAK) inhibitors and colchicine. Schnitzler syndrome should be considered for recurrent chronic urticaria when accompanied by fever, fatigue, rapid weight loss, and poor response to antihistamine treatment. Skin biopsy, bone marrow biopsy, and electrophoresis help confirm the diagnosis. Early diagnosis and treatment can lead to complete resolution of symptoms. Besides interleukin (IL)-1 and IL-6 inhibitors, JAK inhibitors and colchicine may be considered as other choices of treatment.

引用

页码：160 / 163

页数：4

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