Executive summary: Guidelines of care for the management of atopic dermatitis in adults with phototherapy and systemic therapies

被引：6

作者：

Davis, Dawn M. R. ^{[1
,2
]}

Drucker, Aaron M. ^{[3
,4
]}

Alikhan, Ali ^{[5
]}

Bercovitch, Lionel ^{[6
]}

Cohen, David E. ^{[7
]}

Darr, Jennifer M. ^{[8
]}

Eichenfield, Lawrence F. ^{[9
,10
]}

Frazer-Green, Lindsy ^{[11
,19
]}

Paller, Amy S. ^{[12
,13
]}

Schwarzenberger, Kathryn ^{[14
]}

Silverberg, Jonathan I. ^{[15
]}

Singh, Anne Marie ^{[16
]}

Wu, Peggy A. ^{[17
]}

Sidbury, Robert ^{[18
]}

机构：

[1] Mayo Clin, Dept Dermatol, Rochester, MN USA

[2] Mayo Clin, Dept Pediat, Rochester, MN USA

[3] Univ Toronto, Dept Med, Div Dermatol, Toronto, ON, Canada

[4] Womens Coll Hosp, Womens Coll Res Inst, Toronto, ON, Canada

[5] Sutter Med Fdn, Dept Dermatol, Sacramento, CA USA

[6] Brown Univ, Dept Dermatol, Warren Alpert Med Sch, Providence, RI USA

[7] NYU, Ronald O Perelman Dept Dermatol, Grossman Sch Med, New York, NY USA

[8] Natl Jewish Hlth, Dept Pediat, Pediat Behav Hlth, Denver, CO USA

[9] Univ Calif San Diego, Rady Childrens Hosp San Diego, Dept Dermatol, San Diego, CA USA

[10] Univ Calif San Diego, Rady Childrens Hosp San Diego, Dept Pediat, San Diego, CA USA

[11] Amer Acad Dermatol, Rosemont, IL USA

[12] Northwestern Univ, Feinberg Sch Med, Dept Dermatol, Chicago, IL USA

[13] Northwestern Univ, Dept Pediat, Feinberg Sch Med, Chicago, IL USA

[14] Oregon Hlth & Sci Univ, Dept Dermatol, Portland, OR USA

[15] George Washington Univ, Sch Med & Hlth Sci, Dept Dermatol, Washington, DC USA

[16] Univ Wisconsin, Dept Pediat Dermatol & Med Microbiol Immunol, Sch Med & Publ Hlth, Madison, WI USA

[17] Univ Calif, Dept Dermatol, Sacramento, CA USA

[18] Univ Washington, Seattle Childrens Hosp, Dept Pediat, Div Dermatol,Sch Med, Seattle, WA USA

[19] Amer Acad Dermatol, 9500 Bryn Mawr Ave,Suite 500, Rosemont, IL 60018 USA

来源：

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY | 2024年 / 90卷 / 02期

关键词：

atopic dermatitis; azathioprine; biologic; cyclosporine; dupilumab; eczema; JAK inhibitor; methotrexate; phototherapy;

D O I：

10.1016/j.jaad.2023.08.103

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Background: The summarized guidelines update the 2014 recommendations for the management of AD with phototherapy and systemic therapies. Methods: A multidisciplinary workgroup conducted a systematic review and applied the GRADE approach for assessing the certainty of the evidence and formulating and grading recommendations. Results: The workgroup developed 11 recommendations on the management of AD in adults with phototherapy and systemic therapies, including biologics, oral Janus Kinase inhibitors, and other immunomodulatory medications. Conclusions: The evidence supported strong recommendations for the use of dupilumab, tralokinumab, abrocitinib, baricitinib, and upadacitinib and conditional recommendations in favor of using phototherapy, azathioprine, cyclosporine, methotrexate, and mycophenolate, and against the use of systemic corticosteroids. ( J Am Acad Dermatol 2024;90:342-5.)

引用

页码：342 / 345

页数：4

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