Three New Steriodal Saponins from the Rhizomes of Tupistra chinensis Baker

被引：0
|
作者：
He, Xuefeng [1 ,2 ]
Yuan, Xiaofeng [2 ]
Liu, Yang [2 ]
Qiu, Pengcheng [2 ]
Bi, Linlin [2 ]
Tang, Haifeng [2 ]
Lu, Yunyang [2 ]
机构：
[1] Gen Hosp Northern Theater Command, Dept Med Serv, Hlth Serv Planning Sect, Shenyang 110016, Peoples R China
[2] Air Force Med Univ, Sch Pharm, Dept Chinese Mat Med & Nat Med, Xian 710032, Peoples R China
来源：
CHEMISTRY & BIODIVERSITY | 2023年 / 20卷 / 03期
基金：
中国国家自然科学基金;
关键词：
Tupistra chinensis; saponins; structure elucidation; cytotoxicity; POLYHYDROXYLATED STEROIDAL CONSTITUENTS; FUROSTANOL SAPONINS; SPIROSTANOL SAPOGENINS; GEMINAL PROTONS; FRESH RHIZOMES; ROOTS;
D O I：
10.1002/cbdv.202201129
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The phytochemical constituent investigation on the 70 % ethanol extract of the rhizomes of Tupistra chinensis Baker resulted in the isolation of three new steroidal saponins which were named tuchinosides A-C (1-3). Their structures were determined by extensive spectrum analysis and chemical evidence, especially 2D NMR and HR-ESI-MS techniques. In addition, the cytotoxicity of compounds 1-3 against several human cancer cell lines was evaluated.
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页数：9
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