male breast cancer;
breast cancer in men;
targeted screening;
high risk screening;
mammography screening;
mammography in men;
MAMMOGRAPHY;
RISK;
POPULATION;
ULTRASOUND;
CARCINOMA;
BRCA1;
INVOLVEMENT;
PRINCIPLES;
FEMALE;
AREOLA;
D O I:
10.1093/jbi/wbac095
中图分类号:
R73 [肿瘤学];
学科分类号:
100214 ;
摘要:
Breast cancer screening has been highly successful in women in reducing mortality through early detection. In comparison, clinical detection of breast cancer remains the norm in men, and delay in diagnosis is reflected by a persistent survival disparity compared to women despite advances in modern therapy. Male breast cancer presents an interesting dilemma. While mammography is highly sensitive and specific for male breast cancer, routine screening is not justified by the overall low disease incidence. Yet there has been interest in leveraging mammography in targeted screening of men with identifiable risk factors to allow early detection, and early data may support this approach. The purpose of this article is to explore the potential utility of targeted breast cancer screening in men, by examining unique clinical and biologic characteristics of male breast cancers that may lend themselves to mammographic detection. We will also discuss available evidence in screening outcomes in men and summarize recent updates in risk management recommendations in Society guidelines.
机构:
H Lee Moffitt Canc Ctr & Res Inst, Div Breast Imaging, Dept Diagnost Imaging, 12902 USF Magnolia Dr, Tampa, FL 33612 USAH Lee Moffitt Canc Ctr & Res Inst, Div Breast Imaging, Dept Diagnost Imaging, 12902 USF Magnolia Dr, Tampa, FL 33612 USA
Niell, Bethany L.
Freer, Phoebe E.
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机构:
Univ Utah Hosp, Huntsman Canc Inst, Dept Radiol, Div Breast Imaging, 2000 Circle Hope Dr, Salt Lake City, UT 84112 USAH Lee Moffitt Canc Ctr & Res Inst, Div Breast Imaging, Dept Diagnost Imaging, 12902 USF Magnolia Dr, Tampa, FL 33612 USA
Freer, Phoebe E.
Weinfurtner, Robert Jared
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机构:
H Lee Moffitt Canc Ctr & Res Inst, Div Breast Imaging, Dept Diagnost Imaging, 12902 USF Magnolia Dr, Tampa, FL 33612 USAH Lee Moffitt Canc Ctr & Res Inst, Div Breast Imaging, Dept Diagnost Imaging, 12902 USF Magnolia Dr, Tampa, FL 33612 USA
Weinfurtner, Robert Jared
Arleo, Elizabeth Kagan
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机构:
Weill Cornell Med Coll, Weill Cornell Med, Dept Radiol, Div Breast Imaging, 425 East 61st St, New York, NY 10065 USAH Lee Moffitt Canc Ctr & Res Inst, Div Breast Imaging, Dept Diagnost Imaging, 12902 USF Magnolia Dr, Tampa, FL 33612 USA
Arleo, Elizabeth Kagan
Drukteinis, Jennifer S.
论文数: 0引用数: 0
h-index: 0
机构:
H Lee Moffitt Canc Ctr & Res Inst, Div Breast Imaging, Dept Diagnost Imaging, 12902 USF Magnolia Dr, Tampa, FL 33612 USAH Lee Moffitt Canc Ctr & Res Inst, Div Breast Imaging, Dept Diagnost Imaging, 12902 USF Magnolia Dr, Tampa, FL 33612 USA