MicroRNA biosensors for detection of glioblastoma

被引：3

作者：

Fattahi, Mehdi ^{[1
,2
]}

Maghsudlu, Mohadese ^{[3
]}

Razipour, Masoumeh ^{[3
]}

Movahedpour, Ahmad ^{[4
]}

Ghadami, Mohsen ^{[3
]}

Alizadeh, Mehdi ^{[5
]}

Khatami, Seyyed Hossein ^{[5
]}

Taheri-Anganeh, Mortaza ^{[6
]}

Ghasemi, Ehsan ^{[7
]}

Ghasemi, Hassan ^{[7
,8
]}

Aiiashi, Saleh ^{[7
,8
]}

Ghadami, Elham ^{[3
,8
]}

机构：

[1] Duy Tan Univ, Inst Res & Dev, Da Nang, Vietnam

[2] Duy Tan Univ, Sch Engn & Technol, Da Nang, Vietnam

[3] Univ Tehran Med Sci, Sch Med, Dept Med Genet, Tehran, Iran

[4] Behbahan Fac Med Sci, Behbahan, Iran

[5] Shahid Beheshti Univ Med Sci, Sch Med, Dept Clin Biochem, Tehran, Iran

[6] Urmia Univ Med Sci, Cellular & Mol Res Ctr, Cellular & Mol Med Res Inst, Orumiyeh, Iran

[7] Abadan Univ Med Sci, Abadan, Iran

[8] Abadan Univ Med Sci, Clin Biochem, Abadan, Iran

来源：

CLINICA CHIMICA ACTA | 2024年 / 556卷

关键词：

Cancer; Biomarker; Diagnosis; microRNA; ROLLING CIRCLE AMPLIFICATION; INHIBITS CELL-PROLIFERATION; DECREASED EXPRESSION; DOWN-REGULATION; POOR-PROGNOSIS; GLIOMA-CELLS; MIR-21; OLIGONUCLEOTIDE; NANOPARTICLES; APOPTOSIS;

D O I：

10.1016/j.cca.2024.117829

中图分类号：

R446 [实验室诊断]; R-33 [实验医学、医学实验];

学科分类号：

1001 ;

摘要：

Glioblastoma (GBM) is the most common type of malignant brain tumor. The discovery of microRNAs and their unique properties have made them suitable tools as biomarkers for cancer diagnosis, prognosis, and evaluation of therapeutic response using different types of nanomaterials as sensitive and specific biosensors. In this review, we discuss microRNA-based electrochemical biosensing systems and the use of nanoparticles in the evolving development of microRNA-based biosensors in glioblastoma.

引用

页数：7

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