Mitocurcumin Utilizes Oxidative Stress to Upregulate JNK/p38 Signaling and Overcomes Cytarabine Resistance in Acute Myeloid Leukemia

被引:0
|
作者
Gaur, Tarang [1 ,2 ]
Hasan, Syed [1 ,2 ]
机构
[1] Tata Mem Hosp, ACTREC, Mumbai, Maharashtra, India
[2] Homi Bhabha Natl Inst, Mumbai, Maharashtra, India
来源
关键词
acute myeloid leukemia; oxidative stress; JNK; mitocurcumin; cytarabine resistance;
D O I
暂无
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
AML-332
引用
收藏
页码:S291 / S291
页数:1
相关论文
共 50 条
  • [21] Oxalate inhibits renal proximal tubule cell proliferation via oxidative stress, p38 MAPK/JNK, and cPLA2 signaling pathways
    Han, HJ
    Lim, MJ
    Lee, YJ
    AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 2004, 287 (04): : C1058 - C1066
  • [22] N-Acetylcysteine Rescues Hippocampal Oxidative Stress-Induced Neuronal Injury via Suppression of p38/JNK Signaling in Depressed Rats
    Fan, Cuiqin
    Long, Yifei
    Wang, Liyan
    Liu, Xiaohang
    Liu, Zhicheng
    Lan, Tian
    Li, Ye
    Yu, Shu Yan
    FRONTIERS IN CELLULAR NEUROSCIENCE, 2020, 14
  • [23] Cyclosporin A protects JEG-3 cells against oxidative stress-induced apoptosis by inhibiting the p53 and JNK/p38 signaling pathways
    He, Bin
    Li, Qi Yue
    Wu, Yuan Yuan
    Ruan, Jing Ling
    Teng, Xiao Ming
    Li, Da Jin
    Tang, Chuan Ling
    REPRODUCTIVE BIOLOGY AND ENDOCRINOLOGY, 2020, 18 (01)
  • [24] Cyclosporin A protects JEG-3 cells against oxidative stress-induced apoptosis by inhibiting the p53 and JNK/p38 signaling pathways
    Bin He
    Qi Yue Li
    Yuan Yuan Wu
    Jing Ling Ruan
    Xiao Ming Teng
    Da Jin Li
    Chuan Ling Tang
    Reproductive Biology and Endocrinology, 18
  • [25] UVA radiation stimulates ceramide production:: Relationship to oxidative stress and potential role in ERK, JNK, and p38 activation
    Mazière, C
    Conte, MA
    Leborgne, L
    Levade, T
    Hornebeck, W
    Santus, R
    Mazière, JC
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2001, 281 (02) : 289 - 294
  • [26] Isolinderalactone sensitizes oxaliplatin-resistance colorectal cancer cells through JNK/p38 MAPK signaling pathways
    Kwak, Ah-Won
    Park, Jin Woo
    Lee, Seung-On
    Lee, Jin-Young
    Seo, Ji-hye
    Yoon, Goo
    Lee, Mee-Hyun
    Choi, Joon-Seok
    Shim, Jung-Hyun
    PHYTOMEDICINE, 2022, 105
  • [27] Inhibition of p38 MAPK or immunoproteasome overcomes resistance of chronic lymphocytic leukemia cells to Bcl-2 antagonist venetoclax
    Damjan Avsec
    Marja Škrlj Miklavčič
    Tilen Burnik
    Maša Kandušer
    Maruša Bizjak
    Helena Podgornik
    Irena Mlinarič-Raščan
    Cell Death & Disease, 13
  • [28] Inhibition of p38 MAPK or immunoproteasome overcomes resistance of chronic lymphocytic leukemia cells to Bcl-2 antagonist venetoclax
    Avsec, Damjan
    Skrlj Miklavcic, Marja
    Burnik, Tilen
    Kanduser, Masa
    Bizjak, Marusa
    Podgornik, Helena
    Mlinaric-Rascan, Irena
    CELL DEATH & DISEASE, 2022, 13 (10)
  • [29] Targeting STAT5 Signaling Overcomes Resistance to IDH Inhibitors in Acute Myeloid Leukemia through Suppression of Stemness
    Liu, Alex C. H.
    Cathelin, Severine
    Yang, Yitong
    Dai, David L.
    Ayyathan, Dhanoop Manikoth
    Hosseini, Mohsen
    Minden, Mark D.
    Tierens, Anne
    Chan, Steven M.
    CANCER RESEARCH, 2022, 82 (23) : 4325 - 4339
  • [30] Targeting CCL2/CCR2 Signaling Overcomes MEK Inhibitor Resistance in Acute Myeloid Leukemia
    Modak, Rucha V.
    Rebola, Katia G. de Oliveira
    McClatchy, John
    Mohammadhosseini, Mona
    Damnernsawad, Alisa
    Kurtz, Stephen E.
    Eide, Christopher A.
    Wu, Guanming
    Laderas, Ted
    Nechiporuk, Tamilla
    Gritsenko, Marina A.
    Hansen, Joshua R.
    Hutchinson, Chelsea
    Gosline, Sara J. C.
    Piehowski, Paul
    Bottomly, Daniel
    Short, Nicholas
    Rodland, Karin
    McWeeney, Shannon K.
    Tyner, Jeffrey W.
    Agarwal, Anupriya
    CLINICAL CANCER RESEARCH, 2024, 30 (10) : 2245 - 2259