Selinexor Enhances Natural Killer Cell Function Against Multiple Myeloma Cells

被引:0
|
作者
Fisher, Jack G. [1 ]
Doyle, Amber D. P. [1 ]
Graham, Lara V. [1 ]
Forconi, Francesco [2 ]
Cragg, Mark S. [3 ,4 ]
Walker, Christopher J. [5 ]
Khakoo, Salim I. [1 ]
Blunt, Matthew D. [1 ]
机构
[1] Univ Southampton, Sch Clin & Expt Sci, Fac Med, Southampton, Hants, England
[2] Univ Southampton, Sch Canc Sci, Fac Med, Southampton, Hants, England
[3] Univ Southampton, Antibody & Vaccine Grp, Ctr Canc Immunol, Southampton, Hants, England
[4] Univ Southampton, Antibody & Vaccine Grp, Ctr Canc Immunol, Fac Med, Southampton, Hants, England
[5] Karyopharm Therapeut, Newton, MA USA
关键词
D O I
10.1182/blood-2023-179744
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页数:3
相关论文
共 50 条
  • [21] Natural killer cells efficiently target multiple myeloma clonogenic tumor cells
    Leivas, Alejandra
    Risueno, Ruth M.
    Guzman, Alma
    Sanchez-Vega, Laura
    Perez, Manuel
    Megias, Diego
    Fernandez, Lucia
    Alonso, Rafael
    Perez-Martinez, Antonio
    Rapado, Inmaculada
    Martinez-Lopez, Joaquin
    CANCER IMMUNOLOGY IMMUNOTHERAPY, 2021, 70 (10) : 2911 - 2924
  • [22] Natural killer cells efficiently target multiple myeloma clonogenic tumor cells
    Alejandra Leivas
    Ruth M. Risueño
    Alma Guzmán
    Laura Sánchez-Vega
    Manuel Pérez
    Diego Megías
    Lucía Fernández
    Rafael Alonso
    Antonio Pérez-Martínez
    Inmaculada Rapado
    Joaquín Martínez-López
    Cancer Immunology, Immunotherapy, 2021, 70 : 2911 - 2924
  • [23] Cordycepin Enhances the Cytotoxicity of Human Natural Killer Cells against Cancerous Cells
    Chaicharoenaudomrung, Nipha
    Kunhorm, Phongsakorn
    Noisa, Parinya
    BIOLOGICAL & PHARMACEUTICAL BULLETIN, 2023, 46 (09) : 1260 - 1268
  • [24] Clearing soluble MIC reverses the impaired function of natural killer cells from patients with multiple myeloma
    Kim, Sojeong
    Chung, Haerim
    Kwak, Jeong-Eun
    Kim, Yu Ri
    Park, Chung Hyun
    Kim, Yeonhee
    Cheong, June-Won
    Wu, Jennifer
    Shin, Eui-Cheol
    Cho, Hyunsoo
    Kim, Jin Seok
    JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2024, 12 (01)
  • [25] A reversible defect in natural killer T cell function characterizes the progression of premalignant to malignant multiple myeloma
    Dhodapkar, MV
    Geller, MD
    Chang, DH
    Shimizu, K
    Fujii, SI
    Dhodapkar, KM
    Krasovsky, J
    JOURNAL OF EXPERIMENTAL MEDICINE, 2003, 197 (12): : 1667 - 1676
  • [26] EFFECT OF THE IMIDS ON NATURAL KILLER CELLS ACTIVATED AND EXPANDED IN MULTIPLE MYELOMA
    Leivas, A.
    Ramilo, P.
    Guzman, A.
    Valeri, A.
    Garcia-Ortiz, A.
    Rivero, A.
    Martinez-Lopez, J.
    HAEMATOLOGICA, 2018, 103 : 193 - 194
  • [27] Highly activated and expanded natural killer cells for multiple myeloma immunotherapy
    Garg, Tarun K.
    Szmania, Susann M.
    Khan, Junaid A.
    Hoering, Antje
    Malbrough, Paul A.
    Moreno-Bost, Amberly
    Greenway, Amy D.
    Lingo, Joshuah D.
    Li, Xin
    Yaccoby, Shmuel
    Suva, Larry J.
    Storrie, Brian
    Tricot, Guido
    Campana, Dario
    Shaughnessy, John D., Jr.
    Nair, Bijay P.
    Bellamy, William T.
    Epstein, Joshua
    Barlogie, Bart
    van Rhee, Frits
    HAEMATOLOGICA-THE HEMATOLOGY JOURNAL, 2012, 97 (09): : 1348 - 1356
  • [28] Natural killer cell biology and therapy in multiple myeloma: challenges and opportunities
    Bisht, Kamlesh
    Merino, Aimee
    Igarashi, Rob
    Gauthier, Laurent
    Chiron, Marielle
    Desjonqueres, Alexandre
    Smith, Eric
    Briercheck, Edward
    Romee, Rizwan
    Alici, Evren
    Vivier, Eric
    O'Dwyer, Michael
    van de Velde, Helgi
    EXPERIMENTAL HEMATOLOGY & ONCOLOGY, 2024, 13 (01)
  • [29] Targeting Mechanisms for Natural Killer Cell Dysfunction in Patients with Multiple Myeloma
    Jenkins, Misty
    Canfield, Rachael
    Robbins, Michael
    Ritchie, David S.
    Trapani, Joe
    Neeson, Paul
    BLOOD, 2015, 126 (23)
  • [30] Functional Genomic Landscape of Natural Killer Cell Evasion in Multiple Myeloma
    Gandolfi, Sara
    Dufva, Olli
    Huuhtanen, Jani
    Dashevsky, Olga
    Klievink, Jay
    Bouhlal, Jonas
    Sheffer, Michal
    Kankainen, Matti
    Simoes, Ricardo De Matos
    Mustjoki, Satu
    Mitsiades, Constantine S.
    BLOOD, 2021, 138