Patient-reported outcomes from the CodeBreaK 200 phase III trial comparing sotorasib versus docetaxel in KRAS G12C-mutated NSCLC

被引:0
|
作者
Waterhouse, D. M. [1 ]
Rothschild, S. [2 ]
Dooms, C. [3 ]
Mennecier, B. [4 ]
Bozorgmehr, F. [5 ]
Majem, M. [6 ]
van den Heuvel, M. [7 ]
Linardou, H. [8 ,9 ]
Chul-Cho, B. [10 ]
Roberts-Thomson, R. [11 ]
Okamoto, I. [12 ]
Blais, N. [13 ]
Schvartsman, G. [14 ]
Holmskov, K. [15 ]
Chmielewska, I. [16 ]
Forster, M. [17 ]
Stollenwerk, B. [18 ]
Obiozor, C. C. [19 ]
Wang, Y. [19 ]
Novello, S. [20 ]
机构
[1] Dana Farber Canc Inst, Boston, MA USA
[2] Univ Basel, Ctr Comprehens Canc, Med Oncol, Basel, Switzerland
[3] Univ Hosp, Dept Resp Dis, Leuven, Belgium
[4] Univ Hosp Strasbourg, Pulmonol Unit, Strasbourg, France
[5] Univ Hosp Heidelberg, Dept Thorac Oncol, Thoraxklin, Heidelberg, Germany
[6] Hosp Santa Creu & Sant Pau, Med Oncol, Serv Oncol Med, Barcelona, Spain
[7] Radboud Univ Nijmegen, Dept Resp Dis, Med Ctr, Nijmegen, Netherlands
[8] Metropolitan Hosp, Oncol Dept 4, Athens, Greece
[9] Metropolitan Hosp, Comprehens Clin Trials Ctr, Athens, Greece
[10] Yonsei Univ, Div Med Oncol, Dept Internal Med, Yonsei Canc Ctr,Coll Med, Seoul, South Korea
[11] Queen Elizabeth Hosp, Dept Med Oncol, Woodville, SA, Australia
[12] Kyushu Univ Hosp, Fukuoka, Japan
[13] Ctr Hosp Univ Montreal, Dept Med, Montreal, PQ, Canada
[14] Hosp Israelita Albert Einstein, Ctr Oncol & Hematol Einstein Famila Dayan Daycova, Sao Paulo, Brazil
[15] Odense Univ Hosp, Dept Oncol, Odense, Denmark
[16] Med Univ Lublin, Dept Pneumonol Oncol & Allergol, Lublin, Poland
[17] UCL, Canc Inst, London, England
[18] Amgen Europe GmbH, Rotkreuz, Switzerland
[19] Amgen Inc, Thousand Oaks, CA USA
[20] Univ Torino, Dept Oncol, San Luigi Hosp, Turin, Italy
关键词
D O I
暂无
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
4O
引用
收藏
页码:S37 / S38
页数:2
相关论文
共 50 条
  • [41] Long-term outcomes with sotorasib in pretreated KRASp.G12C-mutated NSCLC: 2-year analysis of CodeBreaK100
    Dy, Grace K.
    Govindan, Ramaswamy
    Velcheti, Vamsidhar
    Falchook, Gerald S.
    Italiano, Antoine
    Wolf, Juergen
    Sacher, Adrian G.
    Takahashi, Toshiaki
    Ramalingam, Suresh S.
    Dooms, Christophe
    Kim, Dong-Wan
    Addeo, Alfredo
    Desai, Jayesh
    Schuler, Martin
    Tomasini, Pascale
    Tran, Qui
    Jones, Simon
    Ang, Agnes
    Anderson, Abraham
    Hindoyan, Antreas A.
    Hong, David S.
    Li, Bob T.
    CANCER RESEARCH, 2022, 82 (12)
  • [43] KontRASt-02: A phase III trial investigating the efficacy and safety of the KRASG12C inhibitor JDQ443 vs docetaxel in patients with previously treated, locally advanced or metastatic, KRAS G12C-mutated NSCLC.
    Cappuzzo, Federico
    Castro, Gilberto
    Kang, Jin-Hyoung
    Wu, Yi-Long
    Brustugun, Odd Terje
    Cheema, Parneet Kaur
    Owonikoko, Taofeek K.
    Longin, Anne-Sophie
    Boran, Aislyn
    Duan, Jiawei
    Caparica, Rafael
    Loong, Herbert H. F.
    JOURNAL OF CLINICAL ONCOLOGY, 2023, 41 (16)
  • [44] KontRASt-02: A Phase III Trial Investigating the Efficacy and Safety of the KRASG12C Inhibitor JDQ443 vs. Docetaxel in Patients with Previously Treated, Locally Advanced or Metastatic, KRAS G12C-Mutated NSCLC
    Cappuzzo, F.
    Castro Junior, G.
    Kang, J. H.
    Wu, Y. L.
    Brustugun, O. T.
    Cheema, P. K.
    Owonikoko, T. K.
    Longin, A. S.
    Duan, J.
    Caparica, R.
    Loong, H. H. F.
    Chan, E.
    INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2024, 118 (01): : E14 - E14
  • [45] Sotorasib (soto), panitumumab (pani) and FOLFIRI in the first-line (1L) setting for KRAS G12C-mutated metastatic colorectal cancer (mCRC): Safety and efficacy analysis from the phase Ib CodeBreaK 101 study
    Siena, S.
    Yamaguchi, K.
    Ruffinelli Rodriguez, J. C.
    Corral de la Fuente, E.
    Kuboki, Y.
    Cremolini, C.
    Victoria Ruiz, I.
    Elez Fernandez, M. E.
    Strickler, J. H.
    Furqan, M.
    Bashir, B.
    Nduka, C.
    Hippenmeyer, J.
    Chan, E.
    Xia, C.
    Masuishi, T.
    ANNALS OF ONCOLOGY, 2024, 35 : S429 - S430
  • [46] Trial in progress: A phase III global study of sotorasib, a specific KRAS G12C inhibitor, in combination with panitumumab versus investigator's choice in chemorefractory metastatic colorectal cancer (CodeBreaK 300)
    Paez, D.
    Meriggi, F.
    Cremolini, C.
    Folprecht, G.
    Korantzis, I.
    Chan, E.
    Tran, Q.
    Fakih, M. G.
    ANNALS OF ONCOLOGY, 2022, 33 (07) : S734 - S734
  • [47] A phase 1b study of sotorasib combined with panitumumab as second-line treatment of KRAS G12C-mutated colorectal cancer.
    Yaeger, Rona
    Langer, Corey J.
    Ruffinelli, Jose Carlos
    Fakih, Marwan
    Furqan, Muhammad
    Machiels, Jean-Pascal H.
    Saportas, Yaneth
    Nolte-Hippenmeyer, Jane
    Chan, Emily
    Xia, Caihong
    Masuishi, Toshiki
    JOURNAL OF CLINICAL ONCOLOGY, 2024, 42 (3_SUPPL) : 128 - 128
  • [48] A phase Ib/II study of sotorasib combined with chemotherapy for second-line treatment of KRAS p. G12C-mutated advanced pancreatic cancer
    Mahalingam, Devalingam
    Burns, Michael Charles
    Kalyan, Aparna
    Kircher, Sheetal Mehta
    Kocherginsky, Masha
    Mulcahy, Mary Frances
    Benson, Al Bowen
    JOURNAL OF CLINICAL ONCOLOGY, 2022, 40 (16)
  • [49] Overall survival and exploratory subgroup analyses from the phase 2 CodeBreaK 100 trial evaluating sotorasib in pretreated KRAS p.G12C mutated non-small cell lung cancer.
    Skoulidis, Ferdinandos
    Li, Bob T.
    Govindan, Ramaswamy
    Dy, Grace K.
    Shapiro, Geoffrey
    Bauml, Joshua
    Schuler, Martin H.
    Addeo, Alfredo
    Kato, Terufumi
    Besse, Benjamin
    Anderson, Abraham
    Ang, Agnes
    Ngarmchamnanrith, Gataree
    Tran, Qui
    Velcheti, Vamsidhar
    JOURNAL OF CLINICAL ONCOLOGY, 2021, 39 (15)
  • [50] Patient-reported outcomes from the phase III prostate HYPRO trial: urinary toxicity
    Wortel, R. C.
    Incrocci, L.
    Pos, F. J.
    Smeenk, R. J.
    Krol, A. D. G.
    Aluwini, S.
    Witte, M. G.
    Heijmen, B. J. M.
    Heemsbergen, W. D.
    RADIOTHERAPY AND ONCOLOGY, 2017, 123 : S295 - S297