Responsive PAAM/PEDOT:PSS Hydrogel based Electrochemical Sensor for Glutathione Detection

被引：0
|
作者：
Zhang, Shanshan [1 ]
Zhou, Yue [1 ]
Wang, Dong [1 ]
Li, Tianyu [1 ]
Ye, Xuesong [1 ]
Liang, Bo [1 ]
机构：
[1] Zhejiang Univ, Collage Biomed Engn & Instrument Sci, Biosensor Natl Special Lab, Hangzhou 310027, Peoples R China
来源：
2023 IEEE SENSORS | 2023年
基金：
中国国家自然科学基金;
关键词：
GSH-responsive; conductive hydrogel; electrochemical sensor; CYSTEINE; PROGRESS;
D O I：
10.1109/SENSORS56945.2023.10325184
中图分类号：
R318 [生物医学工程];
学科分类号：
0831 ;
摘要：
Glutathione (GSH) exhibits antioxidant and integrated detoxification effects, providing protection to the liver. Nevertheless, in cases of liver damage or cancerization, the GSH content experiences significant fluctuations. Consequently, GSH can serve as an effective endogenous molecule for aiding the diagnosis and pathological researches of liver diseases. In this study, a GSH-responsive conductive hydrogel was prepared for the quantitative detection of GSH. Through measuring the high-frequency impedance change of the hydrogel during the reaction, the detection of GSH in a wide range (0.1-6 mM) is realized, and the sensor has high sensitivity and good anti-interference performance.
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页数：4
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