Low Susceptibility of Pigs against Experimental Infection with HPAI Virus H5N1 Clade 2.3.4.4b

被引：7
|
作者：
Graaf, Annika [1 ]
Piesche, Ronja [1 ]
Sehl-Ewert, Julia [1 ]
Grund, Christian [1 ]
Pohlmann, Anne [1 ]
Beer, Martin [1 ]
Harder, Timm [1 ]
机构：
[1] Friedrich Loeffler Inst, Suedufer 1017493, Greifswald Insel Riems, Germany
来源：
EMERGING INFECTIOUS DISEASES | 2023年 / 29卷 / 07期
关键词：
INFLUENZA; SWINE;
D O I：
10.3201/eid2907.230296
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
We found that nasal and alimentary experimental exposure of pigs to highly pathogenic avian influenza virus H5N1 clade 2.3.4.4b was associated with marginal viral replication, without inducing any clinical manifestation or pathological changes. Only 1 of 8 pigs seroconverted, pointing to high resistance of pigs to clade 2.3.4.4b infection.
引用
收藏
页码：1492 / 1495
页数：4
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