LONG TERM SAFETY AND EFFICACY OF CAR-T CELL TREATMENT IN REFRACTORY SYSTEMIC LUPUS ERYTHEMATOSUS - DATA FROM THE FIRST SEVEN PATIENTS

被引：6
|
作者：
Taubmann, J. [1 ,2 ,3 ,4 ]
Mueller, F. [2 ,3 ,4 ,5 ]
Boeltz, S. [1 ,2 ,3 ,4 ]
Voelkl, S. [2 ,3 ,4 ,5 ]
Aigner, M. [2 ,3 ,4 ,5 ]
Kleyer, A. [1 ,2 ,3 ,4 ]
Minnopoulou, I. [1 ,2 ,3 ,4 ]
Locatelli, F. [6 ]
D'agostino, M. A. [7 ]
Gary, R. [2 ,3 ,4 ,5 ]
Krestchmann, S. [2 ,3 ,4 ,5 ]
Kharboutli, S. [2 ,3 ,4 ,5 ]
Mougiakakos, D. [2 ,3 ,4 ,5 ,8 ]
Kroenke, G. [1 ,2 ,3 ,4 ]
Andreas, M. [2 ,3 ,4 ,5 ]
Schett, G. [1 ,2 ,3 ,4 ]
机构：
[1] Univ Klinikum Erlangen Nurnberg, Dept Internal Med 3 Rheumatol & Immunol, Erlangen, Germany
[2] Friedrich Alexander Univ Erlangen Nurnberg, Erlangen, Germany
[3] Friedrich Alexander Univ Erlangen Nuremberg, Deutsch Zentrum Immuntherapie DZI, Erlangen, Germany
[4] Univ Klinikum Erlangen, Erlangen, Germany
[5] Univ Klinikum Erlangen Nurnberg, Dept Internal Med 5 Hematol & Oncol, Erlangen, Germany
[6] Osped Pediat Bambino Gesu, Dept Pediat Onco Hematol & Transfus Med, Bambino Gesu, Rome, Italy
[7] Catholica Univ, Div Rheumatol, Fdn Policlin Univ A Gemelli, Sacred Heart, Rome, Italy
[8] Univ Klin Hamatol & Onkol, Hamatol & Onkol, Univ Klinikum Magdeburg AoR, Magdeburg, Germany
来源：
ANNALS OF THE RHEUMATIC DISEASES | 2023年 / 82卷
关键词：
Systemic lupus erythematosus; Remission; Treat to target;
D O I：
10.1136/annrheumdis-2023-eular.3736
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
OP0141
引用
收藏
页码：93 / 94
页数：2
相关论文
共 50 条
  • [41] Long-term efficacy and tolerability of levetiracetam treatment in a patient with epilepsy affected by systemic lupus erythematosus
    Siniscalchi, A.
    Mancuso, F.
    Gallelli, L.
    De Sarro, G.
    EPILEPSIA, 2006, 47 : 46 - 47
  • [42] CD19-Targeted CAR-T Cells in Refractory Systemic Autoimmune Diseases: A Monocentric Experience from the First Fifteen Patients
    Mueller, Fabian
    Taubmann, Jule
    Voelkl, Simon
    Bucci, Laura
    Bergmann, Christina
    Aigner, Michael
    Wilhelm, Artur
    Rothe, Tobias
    Minopoulou, Ioanna
    Knitza, Johannes
    Kharboutli, Soraya
    Spoerl, Silvia
    Vasova, Ingrid
    Werner, Dagmar
    Reimann, Hannah
    Kretschmann, Sascha
    Mougiakakos, Dimitrios
    Kroenke, Gerhard
    Schett, Georg
    Mackensen, Andreas
    BLOOD, 2023, 142
  • [43] Long-term safety profile of belimumab plus standard therapy in patients with systemic lupus erythematosus
    Merrill, Joan T.
    Ginzler, Ellen M.
    Wallace, Daniel J.
    Mckay, James D.
    Lisse, Jeffrey R.
    Aranow, Cynthia
    Wellborne, Frank R.
    Burnette, Michael
    Condemi, John
    Zhong, Z. John
    Pineda, Lilia
    Klein, Jerry
    Freimuth, William W.
    ARTHRITIS AND RHEUMATISM, 2012, 64 (10): : 3364 - 3373
  • [44] Does long term treatment with azathioprine predispose to malignancy and death in patients with systemic lupus erythematosus?
    Nero, P
    Rahman, A
    Isenberg, DA
    ANNALS OF THE RHEUMATIC DISEASES, 2004, 63 (03) : 325 - 326
  • [45] SAFETY AND EFFICACY OF RITUXIMAB IN PATIENTS WITH JUVENILE SYSTEMIC LUPUS ERYTHEMATOSUS: THE PRELIMINARY DATA OF RETROSPECTIVE COHORT STUDY
    Kalashnikova, E.
    Raupov, R.
    Lybimova, N.
    Kuchinskaya, E.
    Kalashnikova, O.
    Chasnyk, V.
    Kornishina, T.
    Snegireva, L.
    Gaidar, E.
    Masalova, V.
    Isupova, E.
    Kaneva, M.
    Dubko, M.
    Likhacheva, T.
    Sorokina, L.
    Kostik, M.
    ANNALS OF THE RHEUMATIC DISEASES, 2022, 81 : 997 - 997
  • [46] Clinical characteristics of systemic lupus erythematosus patients in long-term remission without treatment
    Jakez-Ocampo, J.
    Rodriguez-Armida, M.
    Fragoso-Loyo, H.
    Lima, G.
    Llorente, L.
    Atisha-Fregoso, Y.
    CLINICAL RHEUMATOLOGY, 2020, 39 (11) : 3365 - 3371
  • [47] TREATMENT OF SERVER SYSTEMIC LUPUS-ERYTHEMATOSUS - LONG-TERM RESULTS IN 55 PATIENTS
    JUNGERS, P
    DOUGADOS, M
    TRON, F
    LESAVRE, P
    LEIBOWITCH, J
    NOEL, LH
    BACH, JF
    NOUVELLE PRESSE MEDICALE, 1980, 9 (33): : 2329 - &
  • [48] Clinical characteristics of systemic lupus erythematosus patients in long-term remission without treatment
    J. Jakez-Ocampo
    M. Rodriguez-Armida
    H. Fragoso-Loyo
    G. Lima
    L. Llorente
    Y. Atisha-Fregoso
    Clinical Rheumatology, 2020, 39 : 3365 - 3371
  • [49] CAR-T Cell Therapy for Patients with aggressive Lymphomas Prospect of Long-term Remission
    Arnheim, Katharina
    ONCOLOGY RESEARCH AND TREATMENT, 2019, 42 (12) : 694 - 695
  • [50] Long-Term Safety and Efficacy of Epratuzumab in the Treatment of Moderate-to-Severe Systemic Lupus Erythematosus: Results From an Open-Label Extension Study
    Wallace, D. J.
    Hobbs, K.
    Clowse, M. E. B.
    Petri, M.
    Strand, V.
    Pike, M.
    Merrill, J. T.
    Leszczynski, P.
    Neuwelt, C. M.
    Jeka, S.
    Houssiau, F.
    Keiserman, M.
    Ordi-Ros, J.
    Bongardt, S.
    Kilgallen, B.
    Galateanu, C.
    Kalunian, K.
    Furie, R.
    Gordon, C.
    ARTHRITIS CARE & RESEARCH, 2016, 68 (04) : 534 - 543
12345