Do Patients with Diabetes Mellitus and Polytrauma Continue to Have Worse Outcomes?

被引:0
|
作者
Tebby, James [1 ]
Giannoudis, Vasileios P. [1 ]
Wakefield, Sophia M. [1 ]
Lecky, Fiona [2 ,3 ]
Bouamra, Omar [2 ]
Giannoudis, Peter V. [1 ,4 ]
机构
[1] Univ Leeds, Sch Med, Acad Dept Trauma & Orthopaed, Leeds LS2 9LU, England
[2] Salford Royal NHS Fdn Trust, Trauma Audit & Res Network, Summerfield House, Salford M6 8HD, England
[3] Univ Sheffield, Ctr Urgent & Emergency Care Res, Sch Hlth & Related Res ScHARR, Sheffield S1 4DA, England
[4] Chapel Allerton Hosp, NIHR Leeds Biomed Res Ctr, Leeds LS2 9LU, England
关键词
polytrauma; multiple injuries; diabetes mellitus; complications; mortality;
D O I
10.3390/jcm12103423
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The management of patients with multiple injuries remains challenging. Patients presenting with comorbidities, such as diabetes mellitus, may have additional unpredictable outcomes with increased mortality. Therefore, we aim to investigate the impact of major trauma centres in the UK on the outcomes of polytrauma patients with diabetes. The Trauma Audit and Research Network was used to identify polytrauma patients presenting to centres in England and Wales between 2012 and 2019. In total, 32,345 patients were thereby included and divided into three groups: 2271 with diabetes, 16,319 with comorbidities other than diabetes and 13,755 who had no comorbidities. Despite an overall increase in diabetic prevalence compared to previously published data, mortality was reduced in all groups, but diabetic patient mortality remained higher than in the other groups. Interestingly, increasing Injury Severity Score (ISS) and age were associated with increasing mortality, whereas the presence of diabetes, even when taking into consideration age, ISS and Glasgow Coma Score, led to an increase in the prediction of mortality with an odds ratio of 1.36 (p < 0.0001). The prevalence of diabetes mellitus in polytrauma patients has increased, and diabetes remains an independent risk factor for mortality following polytrauma.
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页数:10
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