Age of breast cancer onset in female BRCA1/2 pathogenic variant carriers is modified by polygenic risk scores

被引:0
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作者
Borde, Julika [1 ]
Ernst, Corinna [1 ]
Laitman, Yael [2 ]
Bluemcke, Britta [1 ]
Niederacher, Dieter [3 ]
Weber-Lassalle, Konstantin [1 ]
Sutter, Christian [4 ]
Rump, Andreas [5 ]
Arnold, Norbert [6 ]
Wang-Gohrke, Shan [7 ]
Horvath, Judit [8 ]
Gehrig, Andrea [9 ]
Schmidt, Gunnar [10 ]
Dutrannoy, Veronique [11 ]
Ramser, Juliane [12 ]
Hentschel, Julia [13 ]
Meindl, Alfons [14 ]
Schroeder, Christopher [15 ]
Wappenschmidt, Barbara [1 ]
Engel, Christoph [16 ]
Kuchenbacker, Karoline [17 ,18 ]
Schmutzler, Rita Katharina [1 ]
Friedman, Eitan [19 ]
Hahnen, Eric [1 ]
机构
[1] Univ Cologne, Fac Med, Ctr Familial Breast & Ovarian Canc, Ctr Integrated Oncol CIO, Cologne, Germany
[2] Sheba Med Ctr, Oncogenet Unit, Tel Hashomer, Israel
[3] Heinrich Heine Univ, Univ Hosp Duesseldorf, Dept Obstet & Gynaecol, Dusseldorf, Germany
[4] Heidelberg Univ, Inst Human Genet, Heidelberg, Germany
[5] Tech Univ Dresden, Inst Clin Genet, Dresden, Germany
[6] Univ Hosp Schleswig Holstein, Inst Clin Mol Biol, Dept Obstet & Gynaecol, Campus Kiel, Kiel, Germany
[7] Univ Hosp Ulm, Dept Obstet & Gynaecol, Ulm, Germany
[8] Univ Hosp Muenster, Inst Human Genet, Munster, Germany
[9] Julius Maximilians Univ, Inst Human Genet, Wurzburg, Germany
[10] Hannover Med Sch, Inst Human Genet, Hannover, Germany
[11] Charite, Inst Med & Human Genet, Berlin, Germany
[12] Tech Univ Munich, Klinikum Rechts Isar, Dept Gynaecol & Obstet, Div Tumor Genet, Munich, Germany
[13] Univ Leipzig Hosp & Clin, Inst Human Genet, Leipzig, Germany
[14] Ludwig Maximilians Univ Munchen, Univ Hosp Munich, Dept Gynaecol & Obstet, Munich, Germany
[15] Univ Tubingen, Inst Med Genet & Appl Genom, Tubingen, Germany
[16] Inst Med Informat Stat & Epidemiol IMISE, Leipzig, Germany
[17] UCL, Div Psychiat, London, England
[18] UCL, UCL Genet Inst, London, England
[19] Tel Aviv Univ, Sackler Sch Med, Tel Aviv, Israel
关键词
D O I
暂无
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
EP13.018
引用
收藏
页码:250 / 250
页数:1
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