Restoring expression of Stathmin-2: a novel strategy to treat TDP-43 proteinopathies

被引:0
|
作者
Menge, Sonja [1 ]
Decker, Lorena [1 ]
Freischmidt, Axel [1 ]
机构
[1] Ulm Univ, Dept Neurol, D-89081 Ulm, Germany
关键词
D O I
10.1038/s41392-023-01533-1
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
[No abstract available]
引用
收藏
页数:2
相关论文
共 50 条
  • [41] Premature polyadenylation-mediated loss of stathmin-2 is a hallmark of TDP-43-dependent neurodegeneration
    Ze’ev Melamed
    Jone López-Erauskin
    Michael W. Baughn
    Ouyang Zhang
    Kevin Drenner
    Ying Sun
    Fernande Freyermuth
    Moira A. McMahon
    Melinda S. Beccari
    Jon W. Artates
    Takuya Ohkubo
    Maria Rodriguez
    Nianwei Lin
    Dongmei Wu
    C. Frank Bennett
    Frank Rigo
    Sandrine Da Cruz
    John Ravits
    Clotilde Lagier-Tourenne
    Don W. Cleveland
    Nature Neuroscience, 2019, 22 : 180 - 190
  • [42] Tau and TDP-43 proteinopathies: kindred pathologic cascades and genetic pleiotropy
    Chornenkyy, Yevgen
    Fardo, David W.
    Nelson, Peter T.
    LABORATORY INVESTIGATION, 2019, 99 (07) : 993 - 1007
  • [43] Epigenetic Methylation and One-Carbon Metabolism in TDP-43 Proteinopathies
    Mahiddine, Farah
    Jackson, Rebecca
    Myland, Alexander
    Agheda, Sheetal
    Walker, Heather
    Kirby, Janine
    Williams, Elizabeth
    Hautbergue, Guillaume
    Highley, Robin
    NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY, 2025, 51
  • [44] Premature polyadenylation-mediated loss of stathmin-2 is a hallmark of TDP-43-dependent neurodegeneration
    Melamed, Ze'ev
    Lopez-Erauskin, Jone
    Baughn, Michael W.
    Zhang, Ouyang
    Drenner, Kevin
    YingSun
    Freyermuth, Fernande
    McMahons, Moira A.
    Beccari, Melinda S.
    Artates, Jon W.
    Ohkubo, Takuya
    Rodriguez, Maria
    Lin, Nianwei
    Wu, Dongmei
    Bennetts, C. Frank
    Rigos, Frank
    Da Cruz, Sandrine
    Ravits, John
    Lagier-Tourenne, Clotilde
    Cleveland, Don W.
    NATURE NEUROSCIENCE, 2019, 22 (02) : 180 - +
  • [45] Data-driven neuropathological staging and subtyping of TDP-43 proteinopathies
    Young, Alexandra L.
    Vogel, Jacob W.
    Robinson, John L.
    McMillan, Corey T.
    Ossenkoppele, Rik
    Wolk, David A.
    Irwin, David J.
    Elman, Lauren
    Grossman, Murray
    Lee, Virginia M. Y.
    Lee, Edward B.
    Hansson, Oskar
    BRAIN, 2023, 146 (07) : 2975 - 2988
  • [46] Reviewing the Potential Links between Viral Infections and TDP-43 Proteinopathies
    Rahic, Zerina
    Buratti, Emanuele
    Cappelli, Sara
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 24 (02)
  • [47] Stathmin 2 is a potential treatment target for TDP-43 proteinopathy in amyotrophic lateral sclerosis
    Liu, Yunqing
    Yan, Dejun
    Yang, Lin
    Chen, Xian
    Hu, Chun
    Chen, Meilan
    TRANSLATIONAL NEURODEGENERATION, 2024, 13 (01)
  • [48] TDP-43 mislocalization drives neurofilament changes in a novel model of TDP-43 proteinopathy
    Atkinson, Rachel
    Leung, Jacqueline
    Bender, James
    Kirkcaldie, Matthew
    Vickers, James
    King, Anna
    DISEASE MODELS & MECHANISMS, 2021, 14 (02)
  • [49] Retrospective neuropathological diagnosis of TDP-43 proteinopathies: Factors affecting immunoreactivity of phosphorylated TDP-43 in fixed post-mortem brain tissue
    Robinson, Andrew C.
    Davidson, Yvonne S.
    Minshull, James
    Lally, Imogen
    Walker, Liam
    Mann, David M. A.
    Roncaroli, Federico
    NEUROPATHOLOGY, 2024, 44 (02) : 173 - 179
  • [50] TDP-43 proteinopathies: pathological identification of brain regions differentiating clinical phenotypes
    Tan, Rachel H.
    Kril, Jillian J.
    Fatima, Manaal
    McGeachie, Andrew
    McCann, Heather
    Shepherd, Claire
    Forrest, Shelley L.
    Affleck, Andrew
    Kwok, John B. J.
    Hodges, John R.
    Kiernan, Matthew C.
    Halliday, Glenda M.
    BRAIN, 2015, 138 : 3110 - 3122